Results 51 to 60 of about 75,116 (210)

Reverse micelles, a system for antibody-catalysed reactions

, 2003
This work presents some aspects of the application of catalytic antibodies in water-in-oil microemulsions (reverse micelles) based on sodium bis-2-(ethylhexyl)sulfosuccinate (AOT) in isooctane.
Friboulet, A., Franqueville, E, Loutrari, H., Loutrari, H, Friboulet, A, Kolisis, F.N, Franqueville, E., Stamatis, H, Kolisis, FN, Mellou, F, Mellou, F., Stamatis, H.   +11 more
core   +1 more source

Stability of acetylcholinesterase (AChE) activity in blood: the effect of the preservative agent

Archives of Forensic Medicine and Criminology
Fluoride anions are believed to inhibit acetylcholinesterase activity, thus there is a possibility that the activity may be affected by blood sampling into vials containing sodium fluoride as an ...
Kaja Tusiewicz, Paweł Szpot, Olga Wachełko, Marcin Zawadzki   +3 more
doaj   +1 more source

The relationship between deltamethrin-induced behavioral changes and acetylcholinesterase activity in zebrafish embryos or larvae based on transcriptome

Frontiers in Veterinary Science
BackgroundDeltamethrin (DM) is a broad-spectrum insecticide that is widely used to control agricultural pests. Recently, DM has posed a potential threat to the health of infants and young children, and this is because of the environmental and food ...
Chunyu Liu, Yantong Guo, Xue Zhang, Hongsong Chen, Maomao Han, Han Wang, Jieyao Niu, Jinfei He, Jingfeng Yang, Wu Dong, Jiangdong Xue   +10 more
doaj   +1 more source

Acetylcholinesterase Inhibitory Activity of Standardized Cannabinoids-rich Fractions [PDF]

Pharmaceutical and Biomedical Research, 2023
Background: Since cannabis has been legally allowed for medicinal purposes in many countries, it has become the most interesting issue, particularly in neurologic disorders, such as Alzheimer’s disease (AD).
Wiwit Suttithumsatid, Jiraporn Kara, Luelak Lomlim, Charassri Nualsri, Pharkphoom Panichayupakaranant   +4 more
doaj  

Design, synthesis and biological evaluation of tricyclic pyrazolo[1,5-c][1,3]benzoxazin-5(5H)-one scaffolds as selective BuChE inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Based on the structural analysis of tricyclic scaffolds as butyrylcholinesterase (BuChE) inhibitors, a series of pyrazolo[1,5-c][1,3]benzoxazin-5(5H)-one derivatives were designed, synthesized and evaluated for their acetylcholinesterase (AChE) and BuChE
Guo-Liang Qiu, Shao-Sheng He, Shi-Chao Chen, Bo Li, Hui-Hui Wu, Jing Zhang, Wen-Jian Tang   +6 more
doaj   +1 more source

Circumdatin D Exerts Neuroprotective Effects by Attenuating LPS-Induced Pro-Inflammatory Responses and Downregulating Acetylcholinesterase Activity In Vitro and In Vivo

Frontiers in Pharmacology, 2020
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder with multifactorial causes, of which systemic inflammation may play a key role to promote neurodegeneration, and acetylcholinesterase (AChE) is a target protein to induce cholinergic ...
Chanjuan Zhang, Likun Hu, Dong Liu, Jian Huang, Wenhan Lin   +4 more
doaj   +1 more source

Nanoparticulate transport of oximes over an in vitro blood-brain barrier model

, 2010
Background: Due to the use of organophosphates (OP) as pesticides and the availability of OP-type nerve agents, an effective medical treatment for OP poisonings is still a challenging problem.
Tikva Vogel, Kreuter, Jörg (Prof. Dr.), Sascha Wien, Zensi, Anja, Kufleitner, Jürgen, Jörg Kreuter, Wien, Sascha, Jürgen Kufleitner, Bungert, Judith, Wagner, Sylvia, Judith Bungert, Dadparvar, Miriam, Vogel, Tikva, Anja Zensi, Sylvia Wagner, Worek, Franz, Miriam Dadparvar, Hagen von Briesen, Briesen, Hagen von, Franz Worek   +19 more
core   +1 more source

Three hydrolases and a transferase: comparative analysis of active-site dynamics via the BioSimGrid database

, 2007
Comparative molecular dynamics (MD) simulations enable us to explore the conformational dynamics of the active sites of distantly related enzymes.
Baaden, Marc, Muan Hong Ngd, Essex, Jonathan, Sansom, MS, Sansom, Mark, Murdock, S, Cox, K, Cox, Katherine, Tai, K, Ng, Muan Hong, Tai, Kaihsu, Jonathan W. Essexc, Steven Johnstonc, Bing Wua, Marc Baadenb, Essex, Jonathan W, Baaden, M, Essex, JW, Essex, Jonathan W., Sansom, Mark S.P., Murdock, Stuart, Wu, Bing, Stuart Murdockc, Johnston, Steven, Fangohr, Hans, Wu, B, Kaihsu Taia, Richard Boardmanc, Ng, MH, Boardman, R, Fangohr, H, Mark S. P. Sansoma, Katherine Coxa, Sansom, Mark S. P., Johnston, S, Hans Fangohrd, Boardman, Richard   +36 more
core   +1 more source

Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon

Molecules, 2009
Four novel bisquaternary aldoxime cholinesterase reactivators differing in their chemical structure were prepared. Afterwards, their biological activity was evaluated for their ability to reactivate acetylcholinesterase (AChE; EC 3.1.1.7) and ...
Daniel Jun, Jana Zdarova Karasova, Miroslav Pohanka, Martina Hrabinova, Kamil Musilek, Martin Paar, Vladimir Cirkva, Jiri Palecek, Kamil Kuca, Lucie Musilova   +9 more
doaj   +1 more source

Avanços sobre a neurotoxicidade induzida pelo pesticida organofosforado malation em modelos experimentais com camundongos [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasO pesticida organofosforado (OF) Malation é um composto utilizado como inseticida em áreas urbanas e rurais. Sabe-se
Silva, Aline Preve da
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