Results 51 to 60 of about 85,087 (299)
Coordination‐Tuned Iridium Single‐Atom Nanozymes Boost Multienzyme Activity for Colorimetric Sensing
Advanced Science, EarlyView.Breaking the coordination symmetry of Ir single‐atom sites through asymmetric Ir–N3S1 engineering tailors interfacial electron transfer, oxygen activation, and multienzyme‐like catalytic pathways. Operando spectroscopy and theoretical modeling uncover the atomic‐level origin of activity enhancement, providing a strategy for designing multifunctional ...
Tao Li +10 more
wiley +1 more source
Anticholinesterase Activities of Different Solvent Extracts of Brewer’s Spent Grain
Foods, 2021 Cholinesterases, involved in acetylcholine catabolism in the central and peripheral nervous system, have been strongly linked with neurodegenerative diseases. Current therapeutic approaches using synthetic drugs present several side effects. Hence, there
Rares I. Birsan +3 more
doaj +1 more source
Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection
Advanced Science, EarlyView.Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse +20 more
wiley +1 more source
CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease
Frontiers in Molecular Neuroscience, 2019 Alzheimer’s disease (AD) is a progressive disease with early degeneration of the central cholinergic neurons. Currently, three of four AD drugs act by inhibiting the acetylcholine (ACh) degrading enzyme, acetylcholinesterase (AChE).
Azadeh Karami +8 more
doaj +1 more source
A Comprehensive Review of Cholinesterase Modeling and Simulation
Biomolecules, 2021 The present article reviews published efforts to study acetylcholinesterase and butyrylcholinesterase structure and function using computer-based modeling and simulation techniques.
Danna De Boer +4 more
doaj +1 more source
, 1998 Organophosphates are valuable insecticides used to control Helicoverpa armigera on cotton in Australia. Those most commonly used for Helicoverpa spp. control are profenofos, parathion-methyl and chlorpyrifos. However, there is an emerging organophosphate-
Gunning, R. V. +2 more
core +1 more source
ACHE (acetylcholinesterase) [PDF]
, 2012 Review on ACHE (acetylcholinesterase), with data on DNA, on the protein encoded, and where the gene is ...
Greenberg, DS, Soreq, H
core +1 more source
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee +3 more
wiley +1 more source
Stability of acetylcholinesterase (AChE) activity in blood: the effect of the preservative agent
Archives of Forensic Medicine and CriminologyFluoride anions are believed to inhibit acetylcholinesterase activity, thus there is a possibility that the activity may be affected by blood sampling into vials containing sodium fluoride as an ...
Kaja Tusiewicz +3 more
doaj +1 more source