Results 201 to 210 of about 64,209 (243)

Austere Moral Ecologies and Artificial Agents

Modern Theology, EarlyView.
Abstract There are underappreciated moral costs for deploying artificially intelligent agents in our present bureaucratically and market‐structured world. Currently, AI systems lack the interiority and mutual vulnerability required for genuine moral relationality.
Manuel Vargas
wiley   +1 more source

New benzimidazole-alkanesulfonate conjugates as cholinesterase inhibitors with in vitro and in silico validation. [PDF]

Sci Rep
Omar MA, Al-Ashmawy AAK, Abd El Salam HA, El-Shiekh RA, Aboulthana WM, Srour AM.   +5 more
europepmc   +1 more source

Full‐length coding sequence analysis of the voltage‐gated sodium channel and acetylcholinesterase genes reveals target‐site mutations and acetylcholinesterase gene duplication in housefly (Musca domestica) populations in Japanese livestock barns

Medical and Veterinary Entomology, EarlyView.
We simultaneously analysed insecticide resistance mutations in VGSC and AChE using NGS and hybridization probe capture in houseflies collected from livestock facilities for the first time. Resistance mutations in both VGSC and AChE were detected in most wild populations, suggesting widespread distribution of resistance genes.
Mikie Nakagawa, Kentaro Itokawa, Nozomi Uemura, Yasuhiro Tomioka, Tsutomu Tanikawa, Kyo Itoyama, Shinji Kasai, Osamu Komagata   +7 more
wiley   +1 more source

Synthesis and Pharmacological Evaluation of Novel 1,5-Disubstituted-3-amino-1,2,4-triazoles Designed as Multitarget Directed Ligands for Alzheimer's Disease Targets. [PDF]

ACS Omega
Franco DP, Caruso L, Grillo DCN, Nadur NF, de Azevedo LL, Pereira TM, da Silva MC, Lacerda RB, Pinheiro PSM, Riger CJ, Kümmerle AE.   +10 more
europepmc   +1 more source

Crime Prevention Through Private Actors: Evidence From a Policy Change at a Large UK Supermarket Chain

Oxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT This paper investigates the effectiveness of private actors in contributing to crime prevention. We leverage well‐publicised increases in security measures, including additional security guards and tagging of goods, by Tesco, a large UK supermarket chain.
Nils Braakmann, Wednesday Croft
wiley   +1 more source

Design, characterization, DFT studies, and molecular docking of new benzofuran-pyrazol-acrylamide hybrids as insecticidal agents against Spodoptera littoralis and Tribolium castaneum. [PDF]

Sci Rep
El-Bana GG, Fouad MR, Deeb ADH, Wahba AM, El-Sayed AF, El-Ghani GEA.   +5 more
europepmc   +1 more source

Compassion‐focused chairwork for voice‐hearing relationships, body triggers and motivational states

Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Purpose This paper aims to build on a recent theoretical and empirical review of CFT for psychosis by outlining a more detailed account of how voice‐hearing perceptions may be generated and triggered, and the implications for clinical practice.
Charles Heriot‐Maitland, Tobyn Bell
wiley   +1 more source

Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1<i>H</i>)-quinoline-<i>O</i>-carbamate derivatives as AChE/MAO-B dual inhibitors for the treatment of Alzheimer's disease. [PDF]

RSC Med Chem
Fu W, Wang K, Chen H, Liu T, Liu X, Jin Q, Tan Z, Dong W, Liu W, Sang Z.   +9 more
europepmc   +1 more source

First Tetraploa Genome and Multi‐Omics Analysis Reveal Key Plant‐Microbe‐Soil Interactions for Salt Tolerance and Yield Improvement of Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT Salinity is a major threat to global agricultural productivity of staple crops such as wheat. Although microbial‐based solutions hold promise for alleviating salinity stress, practical implementation is hindered by insufficient mechanistic characterization of bioinoculants and their interactions with plants.
Cheng‐Wei Qiu, Shuo Zhang, Zi‐Feng Gao, Zhong‐Hua Chen, Chulong Zhang, Mohamed Abdelalim Ali, Feibo Wu   +6 more
wiley   +1 more source