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Achalasia [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2022
Achalasia is characterized by peristaltic failure and incomplete relaxation of the lower esophageal sphincter. The incidence and prevalence of achalasia increase with age, although achalasia can affect all age groups.
Kwangbeom Park, Kee Wook Jung
doaj   +6 more sources

A single-cell transcriptional landscape of immune cells shows disease-specific changes of T cell and macrophage populations in human achalasia

Nature Communications, 2023
Achalasia is a rare motility disorder of the esophagus caused by the gradual degeneration of myenteric neurons. Immune-mediated ganglionitis has been proposed to underlie the loss of myenteric neurons.
Zu-Qiang Liu, Hao Dai, Lu Yao, Wei-Feng Chen, Yun Wang, Li-Yun Ma, Xiao-Qing Li, Sheng-Li Lin, Meng-Jiang He, Ping-Ting Gao, Xin-Yang Liu, Jia-Xin Xu, Xiao-Yue Xu, Ke-Hao Wang, Li Wang, Luonan Chen, Ping-Hong Zhou, Quan-Lin Li   +17 more
doaj   +2 more sources

Response Rate to Treatment of Achalasia Patients With Thyroid Disorders Versus Euthyroid Patients: A Cross‐Sectional Study in Iran [PDF]

JGH Open
Background Achalasia, characterized by impaired esophageal motility, presents a challenge in diagnosis and management. Emerging evidence suggests a potential association between achalasia and thyroid disorders (TD).
Alireza Mehrban, Mehdi Karimi, Fatemeh Ahmadi Hajikolaei, Mohammad Sadra Saghafi, Aydin Hassanpour Adeh, Pegah Refahi, Amir Anushiravani, Javad Mikaeli   +7 more
doaj   +2 more sources

Mapping the experiences of people with achalasia from initial symptoms to long‐term management

Health Expectations, 2021
Background Achalasia is a rare motility disorder affecting the oesophagus, which is associated with a range of symptoms and different treatment strategies. Currently, little is known about people's experiences with achalasia and its management.
Melika Kalantari, Amelia Hollywood, Rosemary Lim, Majid Hashemi   +3 more
doaj   +2 more sources

Role of endoscopy in patients with achalasia [PDF]

Clinical Endoscopy, 2023
Achalasia is an esophageal motility disorder characterized by impaired lower esophageal sphincter relaxation and peristalsis of the esophageal body.
So Young Han, Young Hoon Youn
doaj   +1 more source

Pathogenesis, clinical manifestations, diagnosis, and treatment progress of achalasia of cardia

World Journal of Clinical Cases, 2023
Achalasia cardia, type of esophageal dynamic disorder, is a relatively rare primary motor esophageal disease characterized by the functional loss of plexus ganglion cells in the distal esophagus and lower esophageal sphincter.
Ming-yue Li, Qing-hua Wang, Runsen Chen, Xiao-fang Su, Dong-Yang Wang   +4 more
semanticscholar   +1 more source

Achalasia: The Current Clinical Dilemma and Possible Pathogenesis

Journal of Neurogastroenterology and Motility, 2023
Achalasia is a primary esophageal motility disorder manifested by dysphagia and chest pain that impair patients’ quality of life, and it also leads to chronic esophageal inflammation by food retention and increases the risk of esophageal cancer. Although
Xingyu Jia, Songfeng Chen, Qianjun Zhuang, N. Tan, Mengyu Zhang, Yi Cui, Jinhui Wang, X. Xing, Yinglian Xiao   +8 more
semanticscholar   +1 more source

Psychological burden of achalasia: Patients' screening rates of depression and anxiety and sex differences.

PLoS ONE, 2023
ObjectiveAchalasia is associated with reduced quality of life in affected patients but research regarding the psychological burden of achalasia in terms of depression and anxiety is scarce.
Franz Hanschmidt, Julia Treml, Julia Deller, Nicole Kreuser, Ines Gockel, Anette Kersting   +5 more
doaj   +1 more source

Achalasia is associated with a higher incidence of depression in outpatients in Germany.

PLoS ONE, 2021
Background and aimAchalasia represents a chronic motility disorder of the esophagus featuring an impaired lower esophageal sphincter relaxation and loss of esophageal peristalsis.
Sven H Loosen, Jennis Kandler, Tom Luedde, Karel Kostev, Christoph Roderburg   +4 more
doaj   +1 more source

Esophageal Achalasia: Diagnostic Evaluation

World Journal of Surgery, 2022
A precise diagnosis is key to the successful treatment of achalasia. Barium swallow, upper endoscopy and high-resolution manometry provide the necessary information about a patient’s anatomy, absence of other diseases, and type of achalasia (I, II, III).
F. Riccio, M. Costantini, R. Salvador
semanticscholar   +1 more source