Results 21 to 30 of about 18,013 (209)

Type II achalasia unmasked by EndoFLIP and high-resolution manometry in a child with eosinophilic esophagitis. [PDF]

JPGN Rep
ABSTRACT Eosinophilic esophagitis (EoE) is a chronic immune‐mediated disease characterized by esophageal dysfunction and eosinophilic inflammation. Persistent dysphagia despite histologic remission should prompt evaluation for alternative etiologies. A 10‐year‐old male with asthma and eczema presented with progressive solid food dysphagia, daily non ...
Jaoudeh RARA, Garza JM, Rajendra C.
europepmc   +2 more sources

Intestinal Metaplasia of the Distal Esophagus in a Patient With Untreated Achalasia-An Unusual Case and Review of Literature. [PDF]

Clin Case Rep
ABSTRACT Barrett's esophagus (BE) and achalasia are distinct esophageal disorders with opposing pathophysiologic mechanisms, making their coexistence exceedingly rare. We describe a 51‐year‐old woman who presented with progressive dysphagia, postprandial vomiting, and significant weight loss over 8 months.
Karkra R, Mohsen M, Chowdhury S, Hajifathalian K, Al-Khazraji A.   +4 more
europepmc   +2 more sources

Pulmonary <i>Mycobacterium fortuitum</i> Infection Associated With Achalasia Treated With Peroral Endoscopic Myotomy Alone: A Case Report. [PDF]

Respirol Case Rep
We report a rare case of pulmonary M. fortuitum infection associated with achalasia that improved following treatment of achalasia alone. ABSTRACT Pulmonary infection caused by Mycobacterium fortuitum is uncommon and often occurs in patients with underlying conditions such as achalasia.
Masuda H, Torii R, Yamasaki K, Shingu T, Hata R, Yatera K.   +5 more
europepmc   +2 more sources

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review. [PDF]

DEN Open
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Bhagwat S, Bapaye A.
europepmc   +2 more sources

Psychological burden of achalasia: Patients' screening rates of depression and anxiety and sex differences.

PLoS ONE, 2023
ObjectiveAchalasia is associated with reduced quality of life in affected patients but research regarding the psychological burden of achalasia in terms of depression and anxiety is scarce.
Franz Hanschmidt, Julia Treml, Julia Deller, Nicole Kreuser, Ines Gockel, Anette Kersting   +5 more
doaj   +1 more source

Achalasia is associated with a higher incidence of depression in outpatients in Germany.

PLoS ONE, 2021
Background and aimAchalasia represents a chronic motility disorder of the esophagus featuring an impaired lower esophageal sphincter relaxation and loss of esophageal peristalsis.
Sven H Loosen, Jennis Kandler, Tom Luedde, Karel Kostev, Christoph Roderburg   +4 more
doaj   +1 more source

The role of humoral autoimmunity in gastrointestinal neuromuscular diseases [PDF]

, 2010
PhDDysfunction of the gastrointestinal neuromuscular apparatus (including interstitial cells of Cajal) is presumed to underlie a heterogeneous group of disorders collectively termed gastrointestinal neuromuscular diseases (GINMDs).
Hubball, Andrew William
core   +4 more sources

RNA-sequencing reveals molecular and regional differences in the esophageal mucosa of achalasia patients

Scientific Reports, 2022
Achalasia is an esophageal motility disorder characterized by the functional loss of myenteric plexus ganglion cells in the distal esophagus and lower esophageal sphincter.
Caroline K. Patel, Peter J. Kahrilas, Nathan B. Hodge, Lia E. Tsikretsis, Dustin A. Carlson, John E. Pandolfino, Marie-Pier Tétreault   +6 more
doaj   +1 more source

A single-cell transcriptional landscape of immune cells shows disease-specific changes of T cell and macrophage populations in human achalasia

Nature Communications, 2023
Achalasia is a rare motility disorder of the esophagus caused by the gradual degeneration of myenteric neurons. Immune-mediated ganglionitis has been proposed to underlie the loss of myenteric neurons.
Zu-Qiang Liu, Hao Dai, Lu Yao, Wei-Feng Chen, Yun Wang, Li-Yun Ma, Xiao-Qing Li, Sheng-Li Lin, Meng-Jiang He, Ping-Ting Gao, Xin-Yang Liu, Jia-Xin Xu, Xiao-Yue Xu, Ke-Hao Wang, Li Wang, Luonan Chen, Ping-Hong Zhou, Quan-Lin Li   +17 more
doaj   +1 more source

High-resolution manometric features of achalasia of the cardia

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: Achalasia of the cardia is a common esophageal motility disorder. High-resolution manometry is the gold standard for the diagnosis of achalasia.
Deepanjan Dey, Karuna Datta, DK Dubey, Deep Sharma   +3 more
doaj   +1 more source