Results 1 to 10 of about 22,670 (220)
Nature Reviews Disease Primers, 2022 Achalasia is a rare disorder of the oesophageal smooth muscle characterized by impaired relaxation of the lower oesophageal sphincter (LES) and absent or spastic contractions in the oesophageal body. The key pathophysiological mechanism is loss of inhibitory nerve function that probably results from an autoimmune attack targeting oesophageal myenteric ...
Edoardo Savarino +6 more
exaly +6 more sources
The Lancet, 2014 Achalasia is a rare motility disorder of the oesophagus characterised by loss of enteric neurons leading to absence of peristalsis and impaired relaxation of the lower oesophageal sphincter. Although its cause remains largely unknown, ganglionitis resulting from an aberrant immune response triggered by a viral infection has been proposed to underlie ...
Guy E Boeckxstaens +2 more
exaly +7 more sources
Role of endoscopy in patients with achalasia [PDF]
Clinical Endoscopy, 2023 Achalasia is an esophageal motility disorder characterized by impaired lower esophageal sphincter relaxation and peristalsis of the esophageal body.
So Young Han, Young Hoon Youn
doaj +1 more source
PLoS ONE, 2023 ObjectiveAchalasia is associated with reduced quality of life in affected patients but research regarding the psychological burden of achalasia in terms of depression and anxiety is scarce.
Franz Hanschmidt +5 more
doaj +1 more source
Achalasia is associated with a higher incidence of depression in outpatients in Germany.
PLoS ONE, 2021 Background and aimAchalasia represents a chronic motility disorder of the esophagus featuring an impaired lower esophageal sphincter relaxation and loss of esophageal peristalsis.
Sven H Loosen +4 more
doaj +1 more source
Scientific Reports, 2022 Achalasia is an esophageal motility disorder characterized by the functional loss of myenteric plexus ganglion cells in the distal esophagus and lower esophageal sphincter.
Caroline K. Patel +6 more
doaj +1 more source
Nature Communications, 2023 Achalasia is a rare motility disorder of the esophagus caused by the gradual degeneration of myenteric neurons. Immune-mediated ganglionitis has been proposed to underlie the loss of myenteric neurons.
Zu-Qiang Liu +17 more
doaj +1 more source
Primary versus secondary achalasia: New signs on barium esophagogram
Indian Journal of Radiology and Imaging, 2015 Aim: To investigate new signs on barium swallow that can differentiate primary from secondary achalasia. Materials and Methods: Records of 30 patients with primary achalasia and 17 patients with secondary achalasia were reviewed.
Pankaj Gupta +3 more
doaj +1 more source
Achalasia: A review of Western and Iranian experiences [PDF]
, 2009 Achalasia is a primary motor disorder of the esophagus, in which esophageal emptying is impaired. Diagnosis of achalasia is based on clinical findings. The diagnosis is confirmed by radiographic, endoscopic, and manometric evaluations. Several treatments
Mikaeli, J., Islami, F., Malekzadeh, R.
core +1 more source
High-resolution manometric features of achalasia of the cardia
National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: Achalasia of the cardia is a common esophageal motility disorder. High-resolution manometry is the gold standard for the diagnosis of achalasia.
Deepanjan Dey +3 more
doaj +1 more source