Modeling of influential predictors of gastric cancer incidence rates in Golestan Province, North Iran [PDF]
Golestan province has a reputation for relatively high incidence rates of gastric cancer in Iran. Along with dietary, lifestyle and environmental influential factors, soil selenium and high levels of pesticide used may exert influence in this region. The
Behnampour, N.+3 more
core +1 more source
Endoscopic Prediction of Achalasia: Putting the CART Before the CARS. [PDF]
The novel endoscopic scoring system, the CARS score, demonstrated exceptionally high diagnostic specificity in differentiating patients with achalasia. A classification tree model incorporating the CARS score and hernia presence provides a step‐wise framework for interpreting the endoscopic probability of achalasia.
Li M+11 more
europepmc +2 more sources
Management of Achalasia: Expert Consensus Statements
Achalasia is a motility disorder of the esophagus characterized by absence of peristalsis and failure of relaxation of lower esophagus sphincter. The introduction of high resolution manometry (HRM) and per-oral endoscopic myotomy (POEM) has made a new ...
A Reum Choe, Hye-Kyung Jung
doaj +1 more source
Evaluation and management of achalasia cardia in children: A retrospective observational study
Background: Achalasia cardia is a neuromuscular disorder of unknown etiology characterized by aperistalsis of the body of the esophagus and failure of relaxation of the lower esophageal sphincter.
Nitin Kumar+4 more
doaj +1 more source
Peroral Endoscopic Myotomy for Esophageal Motility Disorders [PDF]
Peroral endoscopic myotomy (POEM) is one of the most clinically successful tunnel-based minimally invasive endoscopic treatments. The classic indications of POEM include achalasia of all types, including failed prior treatments, and expanded indications ...
Jun Young Kim, Yang Won Min
doaj +1 more source
Complications of Endoscopic Pressure Study Integrated System: Review of 1205 Cases in 10 Years' Experience. [PDF]
ABSTRACT Background and Aims The Endoscopic Pressure Study Integrated System (EPSIS) is a novel endoscopic tool to assess lower esophageal sphincter (LES) function by monitoring intragastric pressure (IGP) through insufflation. While previous studies have confirmed its diagnostic utility for LES dysfunction‐related disorders such as gastroesophageal ...
Iwasaki M+9 more
europepmc +2 more sources
Socio-economic status and lifestyle factors are associated with achalasia risk: a population-based case-control study. [PDF]
AIM: To evaluate the association between various lifestyle factors and achalasia risk. METHODS: A population-based case-control study was conducted in Northern Ireland, including n = 151 achalasia cases and n = 117 age- and sex-matched controls ...
Coleman, Helen G.+6 more
core +1 more source
ALLELE-SPECIFIC TRANSCRIPTIONAL ACTIVITY OF THE VARIABLE NUMBER OF TANDEM REPEATS OF THE INDUCIBLE NITRIC OXIDE SYNTHASE GENE IS ASSOCIATED WITH IDIOPATHIC ACHALASIA [PDF]
Background: Polymorphisms of genes involved in the regulation of the immune response are risk factors for achalasia, but their contribution to disease pathogenesis is unknown.
Annese, Vito+12 more
core +1 more source
Surgical therapy (Heller myotomy) is the most effective treatment to relieve dysphagia associated with achalasia. The advent of minimally invasive techniques, specifically the laparoscopic approach, significantly reduced the morbidity of surgical therapy, making it the procedure of choice for most patients who have achalasia.
Todd A, Woltman+2 more
openaire +5 more sources
Peroral Endoscopic Myotomy in Diffuse Thickened Esophageal Wall in an Adolescent
Achalasia is an extremely rare pathology in children. Peroral endoscopic myotomy (POEM) is the gold standard for the surgical treatment of achalasia in adults, but only a limited number of cases of achalasia treatment using POEM in children have been ...
Alexander A. Smirnov+6 more
doaj +1 more source