Results 61 to 70 of about 22,670 (220)

Who Needs Endoscopic Removal of Food Residue From the Esophagus Before Peroral Endoscopic Myotomy for Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction?

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Peroral endoscopic myotomy (POEM) is an established treatment for esophageal achalasia. Despite favorable outcomes, the risk of reflux aspiration during general anesthesia induction in POEM remains a concern. This study aimed to identify the risk factors for food residue in the esophagus before POEM and evaluate the necessity of ...
Masatoshi Kaizuka, Tetsuya Tatsuta, Yohei Sawada, Taka Asari, Shiro Hayamizu, Shinji Oota, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Daisuke Chinda, Tatsuya Mikami, Shinsaku Fukuda, Hirotake Sakuraba   +12 more
wiley   +1 more source

Smooth muscle fascicular reorientation is required for esophageal morphogenesis and dependent on Cdo. [PDF]

, 2013
Postnatal maturation of esophageal musculature involves proximal-to-distal replacement of smooth muscle with skeletal muscle by elusive mechanisms. We report that this process is impaired in mice lacking the cell surface receptor Cdo and identify the ...
Anthony I. Romer, Bai, Chakder, Cole, Cole, Goyal, Goyal, Jagmohan Singh, Kablar, Kang, Kang, Kang, Katori, Kolterud, Krauss, Lagha, Lepper, Litingtung, Lu, Mulieri, Park, Parker, Patapoutian, Ramalho-Santos, Rishniw, Rishniw, Robert S. Krauss, Samarasinghe, Satish Rattan, Spandidos, Sumiyoshi, Takaesu, Tenzen, Wang, Wu, Wörl, Zacharias, Zhang, Zhang, Zhao, Zhao   +40 more
core   +2 more sources

Proteomic Identification of Proteins Suggestive of Immune-Mediated Response or Neuronal Degeneration in Serum of Achalasia Patients

Gut and Liver, 2013
Background/AimsThe primary pathophysiologic abnormality in achalasia is known to be a loss of inhibitory myenteric ganglion cells, which may result from an immune-mediated response or neuronal degeneration.
doaj   +1 more source

Five Advances for Benign Foregut Surgery in the Last 50 Years

World Journal of Surgery, EarlyView.
David I. Watson, Sarah K. Thompson, John G. Hunter, B. Mark Smithers   +3 more
wiley   +1 more source

Is Single‐Session Peroral Endoscopic Myotomy With Fundoplication Safe and Effective in Achalasia? A Systematic Review and Meta‐Analysis

DEN Open, Volume 6, Issue 1, April 2026.
This meta‐analysis of nine studies (202 patients) demonstrates that peroral endoscopic myotomy with fundoplication (POEM‐F) achieves a technical success of 94.8% and significant symptom improvement (Eckardt score reduction from 8.3 to 1.1). Post‐procedural esophagitis occurred in 20.7% and wrap integrity was preserved in 75.7% on follow‐up, supporting ...
Yusuf Kagzi, Abuzar Asif, Srinivas Reddy Puli   +2 more
wiley   +1 more source

Plasma levels of TNF-α, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD)

BMC Gastroenterology, 2019
An elevation of serum inflammatory biomarkers in achalasia patients compared with controls recently was demonstrated. It has not been determined whether the elevation of inflammatory cytokines is unique to achalasia or occurs with other diseases ...
Steven Clayton, Elliot Cauble, Ambuj Kumar, Nirav Patil, Dennis Ledford, Narasaiah Kolliputi, Maria F. Lopes-Virella, Donald Castell, Joel Richter   +8 more
doaj   +1 more source

Current Status of Peroral Endoscopic Myotomy [PDF]

Clinical Endoscopy, 2018
Peroral endoscopic myotomy (POEM) has been established as an optional treatment for achalasia. POEM is an endoluminal procedure that involves dissection of esophageal muscle fibers followed by submucosal tunneling.
Young Kwan Cho, Seong Hwan Kim
doaj   +1 more source

Achalasia

, 2021
Achalasia is a rare motility disorder of the esophagus presenting with symptoms of dysphagia, regurgitation of undigested food, respiratory symptoms (nocturnal cough, recurrent aspiration, pneumonia), chest pain, and weight loss. This chapter focuses solely on idiopathic achalasia.
Boeckxstaens, Guy E., Bredenoord, Albert J.   +1 more
openaire   +3 more sources

Efficacy and Safety of a Revised Gastric Peroral Endoscopic Myo‐Neurotomy Procedure for Bariatric Endoscopy in a Porcine Model

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background Endoscopic sleeve gastroplasty is a minimally invasive and effective treatment for obesity, although gastric mucosa folding and subsequent reduced visibility of the gastric lining raise concerns for some patients. This study evaluates the safety and efficacy of a revised peroral endoscopic myo‐neurotomy (R‐POEM‐N) technique using a ...
Yasushi Yamasaki, Kenta Hamada, Junki Toyosawa, Akinobu Takaki, Takehiro Tanaka, Hiroyuki Okada, Motoyuki Otsuka   +6 more
wiley   +1 more source

Postpartum Acquired Hemophilia A in Two Women With Previously Undiagnosed Carrier Status for von Willebrand Disease Type 2N and Heterozygous p.R854Q Mutation

Haemophilia, EarlyView.
Maria Weise, Tristan Klöter, Maren Keller, Sirak Petros, Christian Pfrepper   +4 more
wiley   +1 more source