Results 81 to 90 of about 44,989 (291)

The Pathogenesis and Management of Achalasia: Current Status and Future Directions

Gut and Liver, 2015
Achalasia is an esophageal motility disorder that is commonly misdiagnosed initially as gastroesophageal reflux disease. Patients with achalasia often complain of dysphagia with solids and liquids but may focus on regurgitation as the primary symptom ...
doaj   +1 more source

Plasma levels of TNF-α, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD)

BMC Gastroenterology, 2019
An elevation of serum inflammatory biomarkers in achalasia patients compared with controls recently was demonstrated. It has not been determined whether the elevation of inflammatory cytokines is unique to achalasia or occurs with other diseases ...
Steven Clayton, Elliot Cauble, Ambuj Kumar, Nirav Patil, Dennis Ledford, Narasaiah Kolliputi, Maria F. Lopes-Virella, Donald Castell, Joel Richter   +8 more
doaj   +1 more source

ALLELE-SPECIFIC TRANSCRIPTIONAL ACTIVITY OF THE VARIABLE NUMBER OF TANDEM REPEATS OF THE INDUCIBLE NITRIC OXIDE SYNTHASE GENE IS ASSOCIATED WITH IDIOPATHIC ACHALASIA [PDF]

, 2016
Background: Polymorphisms of genes involved in the regulation of the immune response are risk factors for achalasia, but their contribution to disease pathogenesis is unknown.
Annese, Vito, BRUZZESE, DARIO, CUOMO, ROSARIO, D'ALESSANDRO, ALESSANDRA, Esposito, Giuseppe, GROSSO, MICHELA, IZZO, PAOLA, PALUMBO, ILARIA, PESCE, MARCELLA, Petruzzelli, Raffaella, SARNELLI, GIOVANNI, Sepulveres, Rossana, Zaninotto, Giovanni   +12 more
core   +1 more source

Concurrent Diagnosis of Superficial Esophageal Cancer and Esophageal Achalasia: A Case Report and Literature Review

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We report a case of a 70‐year‐old woman with esophageal achalasia and concurrent superficial esophageal squamous cell carcinoma. Three adjacent superficial lesions were resected en bloc by endoscopic submucosal dissection (ESD), with no lymphovascular invasion.
Ai Katsumi, Hideki Mori, Noriko Matsuura, Tatsuhiro Masaoka, Yusaku Takatori, Hideomi Tomida, Teppei Akimoto, Hiroko Ando, Motohiko Kato, Takanori Kanai   +9 more
wiley   +1 more source

Impaired Esophageal Motility and Clearance Post-Lung Transplant: Risk For Chronic Allograft Failure [PDF]

, 2017
Objectives: Gastroesophageal reflux is common in patients post-lung transplantation (LTx) and thus considered a risk factor for aspiration and consequently allograft rejection and the development of chronic allograft failure. However, evidence supporting
Almansa, Atkins, Atkins, Blondeau, Cantu, Davis, Davis, Davis, DOvidio, DOvidio, Fisichella, Fisichella, Frazzoni, Frazzoni, Griffin, Hadjiliadis, Johnson, Kahrilas, Mendez, Meyer, Pegna, Ribolsi, Robertson, Roman, Sato, Shay, Stovold, Tutuian, Verleden, Ward, Young   +30 more
core   +1 more source

Achalasia subtypes can be identified with functional luminal imaging probe (FLIP) panometry using a supervised machine learning process

Neurogastroenterology and Motility, 2020
Achalasia subtypes on high‐resolution manometry (HRM) prognosticate treatment response and help direct management plan. We aimed to utilize parameters of distension‐induced contractility and pressurization on functional luminal imaging probe (FLIP ...
D. Carlson, W. Kou, K. Rooney, Alexandra J. Baumann, Erica N. Donnan, Joseph R. Triggs, Ezra N. Teitelbaum, Amy L. Holmstrom, Eric S. Hungness, S. Sethi, P. Kahrilas, J. Pandolfino   +11 more
semanticscholar   +1 more source

Complications of Endoscopic Pressure Study Integrated System: Review of 1205 Cases in 10 Years’ Experience

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background and Aims The Endoscopic Pressure Study Integrated System (EPSIS) is a novel endoscopic tool to assess lower esophageal sphincter (LES) function by monitoring intragastric pressure (IGP) through insufflation. While previous studies have confirmed its diagnostic utility for LES dysfunction‐related disorders such as gastroesophageal ...
Miyuki Iwasaki, Ippei Tanaka, Haruhiro Inoue, Masachika Saino, Kei Ushikubo, Kazuki Yamamoto, Yohei Nishikawa, Kaori Owada, Satoshi Abiko, Mayo Tanabe   +9 more
wiley   +1 more source

Proteomic Identification of Proteins Suggestive of Immune-Mediated Response or Neuronal Degeneration in Serum of Achalasia Patients

Gut and Liver, 2013
Background/AimsThe primary pathophysiologic abnormality in achalasia is known to be a loss of inhibitory myenteric ganglion cells, which may result from an immune-mediated response or neuronal degeneration.
doaj   +1 more source

Severe Recurrent Achalasia Cardia Responding to Treatment of Severe Autoimmune Acquired Haemophilia

Case Reports in Gastroenterology, 2012
Acquired haemophilia A and severe acquired achalasia are both very rare conditions with unknown aetiology. Haemophilia A is a haemorrhagic disease induced by deficiency or malfunction of coagulation factor VIII.
H. Al-Jafar, M. Laffan, S. Al-Sabah, M. Elmorsi, M. Habeeb, F. Alnajar   +5 more
doaj   +1 more source

Serosal patch of the gastroesophageal junction: an experimental study in dogs [PDF]

, 1998
Thirty two dogs were operated on in order to evaluate the mucosal regeneration of the serosal patch at the gastroesophageal junction. The operation began with a cardiotomy involving one centimeter of the esophagus and two centimeters of the stomach ...
Goldenberg, Saul, Magalhães, Albino, Mendelssonh, Paulo   +2 more
core   +3 more sources