Results 111 to 120 of about 8,048,933 (339)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Achievability of the rate-distortion function in binary uniform source coding with side information
, 2016 In this work we consider asymmetric correlation channels and focus on the achievability of the rate-distortion function when the source is binary uniform.
Aleksandra Pizurica +7 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Design and evaluation of an achievability contour display for piloted lunar landing
, 2011 Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Stimpson, Alexander J. (Alexander James)
core
Automatic Digital Modulation Classification Based on Curriculum Learning
Applied Sciences, 2019 Neural network shows great potential in modulation classification because of its excellent accuracy and achievability but overfitting and memorizing data noise often happen in previous researches on automatic digital modulation classifier.
Min Zhang +5 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Towards a more sustainable water future: water governance and Sustainable Development Goal 6 achievability in India [PDF]
, 2017 Humans and the environment in which we live are deeply connected to one another. These interconnections allow for many positive benefits and are foundational to our ability to live on Earth, but also pose many challenges.
Lindamood, Danielle
core
Nature CommunicationsThe absence of catalytic asymmetric methods for synthesizing chiral (hetero)bicyclo[n.1.1]alkanes has hindered their application in new drug discovery.
Wen-Biao Wu +6 more
doaj +1 more source
List-Decoding Capacity of the Gaussian Arbitrarily-Varying Channel
Entropy, 2019 In this paper, we determine the capacity of the Gaussian arbitrarily-varying channel with a (possibly stochastic) encoder and a deterministic list-decoder under the average probability of error criterion.
Fatemeh Hosseinigoki, Oliver Kosut
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source