Results 121 to 130 of about 8,048,933 (339)
Achievability of Asymptotic Minimax Regret in Online and Batch Prediction
, 2013 The normalized maximum likelihood model achieves the minimax coding (log-loss) regret for data of fixed sample size n. However, it is a batch strategy, i.e., it requires that n be known in advance.
Watanabe, Kazuho +2 more
core
Achieving Bidirectionality [PDF]
Proceedings of the 12th conference on Computational linguistics -, 1988 The topic of BIDIRECTIONALITY, using common knowledge in language processing for both analysis and generation, is of both practical and theoretical concern. Theoretically, it is important to determine what knowledge structures can be applied to both. Practically, it is important that a competent natural language system be able to generate outputs that ...
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Financial Achievability Model: Operationalization Case Studies and Analysis [Summary] [PDF]
In a prior research project (BDK83 977-24), the Financial Achievability Model (FAM) was created for the Florida Department of Transportation Research Center.
Tuck, Jason +2 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Achievability Bounds on Unequal Error Protection Codes
Unequal error protection (UEP) codes can facilitate the transmission of messages with different protection levels. In this paper, we study the achievability bounds on UEP by the generalization of Gilbert-Varshamov (GV) bound.
Li, Yuan +6 more
core
Many-User Multiple Access With Random User Activity: Achievability Bounds and Efficient Schemes
We study the Gaussian multiple access channel with random user activity, in the regime where the number of users is proportional to the code length.
core +1 more source