Results 181 to 190 of about 2,768,933 (346)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Achieving memory

open access: yesCoolabah, 2009
Born in Barcelona in 1961. He is a Professor in Fine Arts, at the University of Barcelona. Member of the PhD program in Fine Arts. He has held individual exhibitions of his sculptures and drawings in Barcelona, Madrid, Gerona, The Hague, Amsterdam and Brussels. He currently works on public art projects for a several architects in Barcelona.
openaire   +3 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Health and physical education 2013 [PDF]

open access: yes
In 2013 the National Monitoring Study of Student Achievement assessed student achievement in two learning areas of the New Zealand Curriculum–health and physical education, and mathematics and statistics.
Educational Assessment Research Unit (Otago)   +1 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A Record of Achievement—I [PDF]

open access: green, 1915
Bernhard Hesse
openalex   +1 more source

Achieving a balance [PDF]

open access: yesThe Journal of Laryngology & Otology, 2013
Robin Youngs, Edward A. Fisher
openaire   +2 more sources

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