Results 41 to 50 of about 23,600 (287)
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Multilevel analysis of student and school level factors on students’ academic achievement [PDF]
This study aimed to investigate the factors affecting the academic achievement of students at both school and student levels. Therefore, 600 high school students from 20 schools completed student efficacy scale of Jinks and Morgan's (1999) and personal ...
M. Mohamadi +4 more
doaj +2 more sources
The role of self- and social directed goals in a problem based, collaborative learning context
Students’ learning goals demonstrate much stronger variety than traditional goal orientation models for classroom learning assume, especially when the educational context allows so.
Volet, S. +23 more
core +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
The Effect of Achievement Goal Orientation on the Self-management of College Judo Athletes [PDF]
OBJECTIVES Primary purpose of current research was to examine effect of goal orientation tendency on self control. METHODS Among 2018 college athlets of Korea Judo Association, participants were recruited through convinence sampling. Except for insincere
Sungbae Park
doaj +1 more source
In order to study the relation between miners’ achievement goal orientation and safety performance, avoid unsafe behavior and improve miners’ safety performance, this paper uses the chain intermediary effect to study the early warning mechanism of ...
LI Bin, LI Jizu
doaj +1 more source
Achievement motivation of adult learners in Hong Kong- An exploratory study [PDF]
This thesis is focused on the question of motivation among adult students and the ways in which it can be theorised and investigated. The idea was prompted by three areas of concern.
Lee, Eva Wai-Chi
core
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora +4 more
wiley +1 more source
Trace additions of Sn and Sr combined with a two‐step aging treatment are shown to enhance the microstructure and performance of Al–Zr–Sc conductor alloys. Strength and electrical conductivity increase concurrently through accelerated precipitation of fine Al3(Sc, Zr) precipitates and improved dislocation resistance, offering a cost‐effective pathway ...
Quan Shao +3 more
wiley +1 more source

