Results 31 to 40 of about 45,345 (258)

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

The economic cost and patient-reported outcomes of chronic Achilles tendon ruptures

Journal of Experimental Orthopaedics, 2020
Purpose While most Achilles tendon ruptures are dramatic and diagnosed quickly, some are missed, with a risk of becoming chronic. A chronic Achilles tendon rupture is defined as a rupture that has been left untreated for more than 4 weeks. By mapping the
Niklas Nilsson, Katarina Nilsson Helander, Eric Hamrin Senorski, Anna Holm, Jón Karlsson, Mikael Svensson, Olof Westin   +6 more
doaj   +1 more source

Novel classification of Achilles tendon ruptures

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
In the literature, the treatment of patients with Achilles tendon ruptures begins with diagnosis and diagnosis. Depending on the classification of Achilles tendon rupture, treatment tactics are determined.
Yu. D. Kim, Yu. I. Bardovskaya, S. N. Romanova, A. S. Pankratov, D. S. Shitikov   +4 more
doaj   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Research Progress of Biodegradable Polymers in Repairing Achilles Tendon Injury

Frontiers in Materials, 2022
Achilles tendon injury has become a common sports injury clinically, and its treatment and rehabilitation are essential, while the regenerative capacity of the Achilles tendon in adult mammals is limited.
Jinchi Zhang, Jinchi Zhang, Wange Wang, Xinan Zhang, Liqun Yang, JinChao Zhang   +5 more
doaj   +1 more source

Illuminating the Intracellular World: Breakthroughs in Nanoscale Optoelectronics

Advanced Electronic Materials, EarlyView.
This perspective explores optoelectronic biointerfaces spanning macroscale flexible devices to nanoscale intracellular systems, emphasizing their integration across dimensions. It examines capacitive, Faradaic, and photothermal mechanisms that enable light‐driven control of cellular activity and highlights key material and design challenges in ...
Tania Assaf, Menahem Y. Rotenberg
wiley   +1 more source

Achilles Tendon Allograft Incorporated with Autologous Mesenchymal Stem Cells

Foot & Ankle Orthopaedics, 2017
Category: Basic Sciences/Biologics Introduction/Purpose: Achilles tendinopathy and rupture are common and generally can heal without aggressive intervention.
Zijun Zhang MD, Michael Aynardi MD, Talal Zahoor MD, Lew Schon MD   +3 more
doaj   +1 more source

Inflammatory and Metabolic Alterations of Kager's Fat Pad in Chronic Achilles Tendinopathy. [PDF]

PLoS ONE, 2015
Achilles tendinopathy is a painful inflammatory condition characterized by swelling, stiffness and reduced function of the Achilles tendon. Kager's fat pad is an adipose tissue located in the area anterior to the Achilles tendon.
Jessica Pingel, M Christine H Petersen, Ulrich Fredberg, Søren G Kjær, Bjørn Quistorff, Henning Langberg, Jacob B Hansen   +6 more
doaj   +1 more source

Achilles tendon thickening does not affect elasticity and functional outcome after surgical repair of Achilles rupture: A retrospective study

Chinese Journal of Traumatology, 2023
Purpose: Previous studies have confirmed that Achilles tendon occurs Achilles thickening after repair surgery of the rupture. Although this mechanism has been elucidated in the laboratory, there are few reports on its impact on clinical function.
Chen-Xi Wu, Chang-Yue Xiong, Lu Bai, Su-Meng Chen, Yu-Xin Yan, Lu Wang, Xin-Tao Zhang   +6 more
doaj   +1 more source