Results 41 to 50 of about 36,214 (270)

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

open access: yesAdvanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang   +11 more
wiley   +1 more source

Current treatment concepts for Achilles tendon rupture

open access: yesTzu Chi Medical Journal
Achilles tendon rupture is a common and primary cause of lower limb tendon injury suffered during sports-related activities. The causes of Achilles tendon rupture include the calf muscle and tendon overuse, poor tendon quality, and various medical ...
Chen-Chie Wang   +4 more
doaj   +1 more source

Long harvest of the flexor hallucis longus tendon in reconstructive foot & ankle surgery: A technique guide

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases, 2022
Reconstruction of the Achilles tendon for insertional disease, acute and chronic ruptures, severe mangling limb trauma, and tendon loss from necrotizing infections often results in a significant reconstructive challenge.
Christopher Bibbo, DO, DPM, FACS, FAAOS, FACFAS
doaj   +1 more source

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

open access: yesAdvanced Science, EarlyView.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans   +8 more
wiley   +1 more source

Advanced glycation end products impair the repair of injured tendon: a study in rats

open access: yesBMC Musculoskeletal Disorders
Background The AGEs levels in tissues of diabetics and elderly tend to be higher than in normal individuals. This study aims to determine the effects of AGEs on Achilles tendon repair.
Juan Yang, Jirui He, Ling Yang
doaj   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Primary plastics of Achilles tendon by plantar muscle tendon for the prevention of repeated ruptures (experimental research)

open access: yesActa Biomedica Scientifica, 2013
The most important requirement to Achilles tendon suture is its ability to hold loading both in postoperative and. in rehabilitation period. The research was aimed, at the comparison of strength of classic intertendon suture of Achilles tendon and ...
N. S. Ponomarenko   +6 more
doaj  

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

open access: yesAdvanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim   +7 more
wiley   +1 more source

Decellularised amniotic membrane-TDSCs composite promotes Achilles tendon healing

open access: yesScientific Reports
Adhesions and poor healing are major complications after Achilles tendon injury, and there is no effective solution to this problem. The purpose of this study is to determine whether the biomimetic peritoneurosis can solve the above problems in the ...
Xufeng Mao   +7 more
doaj   +1 more source

Regional variations in incidence and treatment trends of Achilles tendon ruptures in Finland: a nationwide study

open access: yesActa Orthopaedica
Background and purpose: The aim of our study was to assess the regional variations in Achilles tendon rupture incidence and treatment methods in Finland during the period 1997–2019.
Marjukka Hallinen   +4 more
doaj   +1 more source

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