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Achilles tendon ruptures [PDF]
The incidence of acute Achilles tendon ruptures is on the rise. This is thought to be due to the increasing number of middle-aged persons participating in athletic and/or strenuous activity. Ruptures of the Achilles tendon can be severely debilitating, with deficits seen years after the initial incident.
Greg Kirwan, David Pedowitz
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A 60-year-old man presented to the emergency department complaining of acute onset posterior ankle pain. He reported playing tennis earlier in the afternoon when he suddenly stopped and pivoted, noting a “pop” sensation and pain to the right posterior ankle. The pain was sharp and increased with movement.
Stickles, Sean P.+3 more
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Chronic Achilles Tendon Rupture [PDF]
Background:The Achilles tendon, the largest and strongest tendon in the human body, is nevertheless one of the tendons which most commonly undergoes a complete subcutaneous tear. Achilles tendon ruptures are especially common in middle aged men who occasionally participate in sport.
Maffulli N, Via AG, Oliva F
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Achilles tendon rupture. [PDF]
The Achilles tendon (AT) is the largest tendon in the human body, but it is also the one that frequently undergoes a complete subcutaneous tear. Men are more frequently affected than women, in particular between 30–40 years old. An AT tear is usually the end result of an asymptomatic process of failed heling typical of tendinopathy.
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The Incidence of Achilles Tendon Rupture [PDF]
During the years 1950-1973, 229 cases of Achilles tendon rupture were diagnosed in the city of Malmö. More than half of the injuries were caused by sporting activities, the most common being badminton and football (soccer). Ruptures caused by injuries other than sports injuries were found in considerably older subjects.
Nils E. Westlin+2 more
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Abstract Modulation of bone marrow adipose tissue (BMAT) with prolonged inactivity was reported in haemopoietic but not in non‐haemopoietic bones. This prospective randomized controlled trial submitted 16 men and 8 women to 60 days of 6° head‐down‐tilt bed rest.
Tammy Liu+5 more
wiley +1 more source
Abstract figure legend The majority of L4–L5 dorsal root ganglion cells innervating the triceps surae muscles of healthy rats expressed TRPC6 channels. In decerebrated rats, pharmacological inhibition of TRPC6 channels by injection of antagonists (SAR7334 or BI‐749327) into the arterial supply of the triceps surae muscles inhibited the exercise pressor
Guillaume P. Ducrocq+5 more
wiley +1 more source
Abstract figure legend The role of lactate and hydrogen ions in evoking the metabolic component of the exercise pressor reflex was studied in rats with either a functional pygm gene (pygm+/+) or with a non‐functional “knocked out” pygm gene (pygm−/−). The pygm gene is responsible for producing the myophosphorylase enzyme which catalyses the breakdown ...
Guillaume P. Ducrocq+3 more
wiley +1 more source
Abstract figure legend Motor unit firing properties of the medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SO) muscles were assessed using high‐density surface electromyography (HD‐sEMG) during isometric plantarflexion contractions at 10%, 40%, and 70% maximal voluntary contraction (MVC) in individuals with non‐insertional Achilles ...
Ignacio Contreras‐Hernandez+5 more
wiley +1 more source
Exploring cellular changes in ruptured human quadriceps tendons at single‐cell resolution
Abstract figure legend This study explores the cellular landscape of healthy and ruptured quadriceps tendons using single nucleus RNA sequencing. While a range of stromal and immune cell types and subsets were identified, the data indicate that fibroblasts and endothelial cells are the main drivers of the early injury response within ruptured ...
Jolet Y. Mimpen+15 more
wiley +1 more source