Using Platelet-Rich Plasma to Reverse the Effects of Tendinopathy and Prevent Tendon Re-rupture after Surgery in Athletes: The Search for a Standardized Protocol [PDF]
30-50% of all lesions amateur and professional sports players will experience during activity are related to the tendon. Moreover, the incidence of tendinopathy, a precursor to tendon rupture, is much higher in both of these groups due to excessive ...
Patel, Shiv
core +1 more source
Ciprofloxacin reduces the stimulation of prostaglandin E2 output by interleukin-1 in human tendon-derived cells [PDF]
Fluoroquinolone antibiotics such as ciprofloxacin can induce tendon pathology and have various effects on tendon-derived cells in culture. We are investigating whether ciprofloxacin modifies signalling responses in tendon cells.
Corps, AN +5 more
core +1 more source
The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair
Synthesis of an innovative three‐layer composite antiadhesion barrier (plasmid DNA@E–H–E′) is schematically illustrated, highlighting its reactive‐oxygen‐species‐responsive, unidirectional interleukin‐37 delivery to enhance fibroblast autophagy, thereby effectively preventing tendon adhesion and promoting scarless tendon repair.
Zhenyu Sun +5 more
wiley +1 more source
The role of detraining in tendon mechanobiology [PDF]
INTRODUCTION: Several conditions such as training, aging, estrogen deficiency and drugs could affect the biological and anatomo-physiological characteristics of the tendon.
Aldini, Nicol\uf2 Nicoli +7 more
core +3 more sources
The mechanism diagram reveals that the formation of trauma‐induced heterotopic ossification (HO) is accompanied by the polarization of macrophages toward the M1 phenotype. Additionally, the extracellular vesicles secreted by M1 macrophages, which contain periostin (POSTN), directly bind to PTK7 in tendon‐derived stem cells (TDSCs).
Hang Liu +9 more
wiley +1 more source
Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon [PDF]
To profile the messenger RNA (mRNA) expression for the 23 known genes of matrix metalloproteinases (MMPs), 19 genes of ADAMTS, 4 genes of tissue inhibitors of metalloproteinases (TIMPs), and ADAM genes 8, 10, 12, and 17 in normal, painful, and ruptured ...
Alfredson +73 more
core +1 more source
Age and tightness of repair are predictors of heel-rise height after Achilles tendon rupture [PDF]
Background: Achilles tendon rupture leads to weakness of ankle plantarflexion. Treatment of Achilles tendon rupture should aim to restore function while minimizing weakness and complications of management.
Brorsson, Annelie +5 more
core +2 more sources
ABSTRACT Extensor mechanism autografts used for anterior cruciate ligament reconstruction, namely bone‐patellar tendon‐bone (BPTB) and quadriceps tendon (QT), may result in harvest‐site tendon elongation. Extended field of view (EFOV) ultrasound imaging has the potential to evaluate changes in tendon length, but the reliability and validity of these ...
Andrew Sprague, George Raum, Naoaki Ito
wiley +1 more source
Developing a patient decision aid for Achilles tendon rupture management: a mixed-methods study
Objective To develop and user-test a patient decision aid portraying the benefits and harms of non-surgical management and surgery for Achilles tendon ruptures.Design Mixed methods.Setting A draft decision aid was developed using guidance from a ...
Ian A Harris +9 more
doaj +1 more source
The Incidence of Achilles Tendon Rupture [PDF]
During the years 1950-1973, 229 cases of Achilles tendon rupture were diagnosed in the city of Malmö. More than half of the injuries were caused by sporting activities, the most common being badminton and football (soccer). Ruptures caused by injuries other than sports injuries were found in considerably older subjects.
Nils E. Westlin +2 more
openaire +3 more sources

