Results 1 to 10 of about 1,127,600 (287)

The classification and therapeutic applications of molecular motors

European Journal of Medicinal Chemistry Reports, 2021
The molecular motors are protein molecules which can be teamed up to form the active mobile nanomachine with special functions. As a new type of therapeutic target different from normal enzymes or receptors, molecular motor plays a unique role in the ...
Mingyuan Li, Yuan Li, Lin Jia, Shiqin Li, Meng Li, Guang Yang, Nan Liu, Hongmeng Ren, Mingqi Mou, Aiping Zheng, Hua Sun   +10 more
doaj   +1 more source

Promoting Students’ Scientific Habits of Mind and Chemical Literacy Using the Context of Socio-Scientific Issues on the Inquiry Learning

Frontiers in Education, 2021
This quasi-experimental study used a pre-/posttest design to investigate student’s scientific habits of mind (SHOM) and chemical literacy. There were 32 students of the 11th grade selected for the experimental and control class. They were taken by random
Antuni Wiyarsi, A. K. Prodjosantoso, Anggiyani R. E. Nugraheni   +2 more
doaj   +1 more source

Cerebrospinal fluid electrolytes and acid-base in diabetic patients

Translational Neuroscience, 2021
Diabetes mellitus (DM) has detrimental effects on the function of microvascular beds, resulting in blood–brain barrier (BBB) dysfunction. The objective of the study was to investigate whether DM affects the brain physiology through composition of ...
Liao Chia-Chih, Hou Te-Hsin, Yu Huang-Ping, Li Allen, Liu Fu-Chao   +4 more
doaj   +1 more source

High Dietary Cation and Anion Difference and High-Dose Ascorbic Acid Modify Acid–Base and Antioxidant Balance in Dairy Goats Fed under Tropical Conditions

Animals, 2023
High ambient temperature (HTa) causes acid–base imbalance and systemic oxidative stress, and this may indirectly affect the mammary gland. Furthermore, HTa induces intracellular oxidative stress, which has been proposed to affect cell metabolism directly.
Sapon Semsirmboon, Dang Khoa Do Nguyen, Narongsak Chaiyabutr, Sutthasinee Poonyachoti, Thomas A. Lutz, Sumpun Thammacharoen   +5 more
doaj   +1 more source

Analysis Students’ Scientific Explanation Skills Using Explanation Driven Inquiry Learning on Acid-Base Topic

JTK (Jurnal Tadris Kimiya), 2021
This study analyzes students' scientific explanation skills using explanation driven inquiry (EDI) learning on acid-base topics. The method used a quasi-experimental design with a posttest-only control group design.
Oktavia Sulistina, Hesti Puspitasari, Dedek Sukarianingsih   +2 more
doaj   +1 more source

Development of Integrated Assessment Instrument to Measure Critical Thinking Skills and Self-Efficiency in Acid-Base Concept

JTK (Jurnal Tadris Kimiya), 2021
The purpose of this research is to describe the stages of developing and validating a product which includes content validity and constructs validity.
Nuryuliana Nuryuliana, Anti Kolonial Prodjosantoso   +1 more
doaj   +1 more source

Acid-Base Homeostasis [PDF]

Clinical Journal of the American Society of Nephrology, 2015
Acid-base homeostasis and pH regulation are critical for both normal physiology and cell metabolism and function. The importance of this regulation is evidenced by a variety of physiologic derangements that occur when plasma pH is either high or low. The kidneys have the predominant role in regulating the systemic bicarbonate concentration and hence ...
L Lee, Hamm, Nazih, Nakhoul, Kathleen S, Hering-Smith   +2 more
openaire   +2 more sources

NBCe1-B/C-knockout mice exhibit an impaired respiratory response and an enhanced renal response to metabolic acidosis

Frontiers in Physiology, 2023
The sodium-bicarbonate cotransporter (NBCe1) has three primary variants: NBCe1-A, -B and -C. NBCe1-A is expressed in renal proximal tubules in the cortical labyrinth, where it is essential for reclaiming filtered bicarbonate, such that NBCe1-A knockout ...
Clayton T. Brady, Aniko Marshall, Chen Zhang, Chen Zhang, Mark D. Parker, Mark D. Parker   +5 more
doaj   +1 more source

F7 and topotecan co-loaded thermosensitive liposome as a nano-drug delivery system for tumor hyperthermia

Drug Delivery, 2020
In order to enhance the targeting efficiency and reduce anti-tumor drug’s side effects, topotecan (TPT) and F7 were co-loaded in thermosensitive liposomes (F7-TPT-TSL), which show enhanced permeability and retention in tumors, as well as local controlled
Chunyang Du, Shuangshuang Li, Yuan Li, Hervé Galons, Na Guo, Yuou Teng, Yongmin Zhang, Mingyuan Li, Peng Yu   +8 more
doaj   +1 more source

DUAL SITUATED LEARNING MODEL AS REMEDIAL TEACHING TO ACID-BASE MISCONCEPTIONS

EDUSAINS, 2022
The research aimed to determine whether or not there is an acid-base misconception using a three-tier multiple choice and the effectiveness of using DSLM in reducing these misconceptions.
Mela Yuliyanti, Sulistyo Saputro, Ashadi Ashadi   +2 more
doaj   +1 more source