Results 1 to 10 of about 233,323 (358)

Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes

open access: yesCell Metabolism, 2020
The safety and efficacy of anti-diabetic drugs are critical for maximizing the beneficial impacts of well-controlled blood glucose on the prognosis of individuals with COVID-19 and pre-existing type 2 diabetes (T2D).
Haomiao Li, Lijin Lin, Jiahong Xia
exaly   +2 more sources

Metabolic Acidosis in CKD: A Review of Recent Findings

open access: yesKidney Medicine, 2021
Metabolic acidosis is fairly common in patients with chronic kidney disease (CKD). The prevalence of metabolic acidosis increases with worsening kidney function and is observed in ∼40% of those with stage 4 CKD.
Kalani Raphaël, Michal Melamed
exaly   +2 more sources

Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis

open access: yesNeoplasia: An International Journal for Oncology Research, 2022
Regions of low oxygen (hypoxia) are found in >50% of breast tumours, most frequently in the more aggressive triple negative breast cancer subtype (TNBC). Metastasis is the cause of 90% of breast cancer patient deaths. Regions of tumour hypoxia tend to be
Christopher Paul Carroll   +8 more
doaj   +1 more source

Evaluation of Megasphaera elsdenii supplementation on rumen fermentation, production performance, carcass traits and health of ruminants: a meta-analysis [PDF]

open access: yesAnimal Bioscience, 2023
Objective This study was conducted to evaluate the use of Megasphaera elsdenii (M. elsdenii) as a probiotic on rumen fermentation, production performance, carcass traits and health of ruminants by integrating data from various related studies using meta ...
Irwan Susanto   +5 more
doaj   +1 more source

The Role of Acidosis in the Pathogenesis of Severe Forms of COVID-19

open access: yesBiology, 2021
Simple Summary Recently, several studies have shown that acidosis, which is increased acidity in the blood and other body tissues, is often associated with severe COVID-19.
Yury Nechipurenko   +7 more
semanticscholar   +1 more source

Metabolic diseases in cattle

open access: yesВетеринария сегодня, 2021
The main trend in the development of dairy farming in the Russian Federation suggests maximising milk yield and reducing milk net cost. The economic effectiveness of industrial dairy farming is largely determined by adequate feeding, as well as effective
V. A. Mischenko   +4 more
doaj   +1 more source

TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells

open access: yesNature Communications, 2020
Acidosis, a common characteristic of the tumor microenvironment, is associated with alterations in metabolic preferences of cancer cells and progression of the disease. Here we identify the TGF-β2 isoform at the interface between these observations.
C. Corbet   +13 more
semanticscholar   +1 more source

Dose of Bicarbonate to Maintain Plasma pH During Maximal Ergometer Rowing and Consequence for Plasma Volume

open access: yesFrontiers in Physiology, 2022
Rowing performance may be enhanced by attenuated metabolic acidosis following bicarbonate (BIC) supplementation. This study evaluated the dose of BIC needed to eliminate the decrease in plasma pH during maximal ergometer rowing and assessed the ...
Henning Bay Nielsen   +3 more
doaj   +1 more source

Etiology of lactic acidosis in malaria

open access: yesPLoS Pathogens, 2021
Lactic acidosis and hyperlactatemia are common metabolic disturbances in patients with severe malaria. Lactic acidosis causes physiological adverse effects, which can aggravate the outcome of malaria.
Hendrik Possemiers   +2 more
semanticscholar   +1 more source

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