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Lactic Acidosis [PDF]

open access: yesNew England Journal of Medicine, 2014
Lactic acidosis results from the accumulation of lactate and protons in the body fluids and is often associated with poor clinical outcomes. The effect of lactic acidosis is governed by its severity and the clinical context. Mortality is increased by a factor of nearly three when lactic acidosis accompanies low-flow states or sepsis,1 and the higher ...
Nicolaos E Madias
exaly   +10 more sources

Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis

open access: yesNeoplasia: An International Journal for Oncology Research, 2022
Regions of low oxygen (hypoxia) are found in >50% of breast tumours, most frequently in the more aggressive triple negative breast cancer subtype (TNBC). Metastasis is the cause of 90% of breast cancer patient deaths. Regions of tumour hypoxia tend to be
Christopher Paul Carroll   +8 more
doaj   +1 more source

Evaluation of Megasphaera elsdenii supplementation on rumen fermentation, production performance, carcass traits and health of ruminants: a meta-analysis [PDF]

open access: yesAnimal Bioscience, 2023
Objective This study was conducted to evaluate the use of Megasphaera elsdenii (M. elsdenii) as a probiotic on rumen fermentation, production performance, carcass traits and health of ruminants by integrating data from various related studies using meta ...
Irwan Susanto   +5 more
doaj   +1 more source

Metabolic diseases in cattle

open access: yesВетеринария сегодня, 2021
The main trend in the development of dairy farming in the Russian Federation suggests maximising milk yield and reducing milk net cost. The economic effectiveness of industrial dairy farming is largely determined by adequate feeding, as well as effective
V. A. Mischenko   +4 more
doaj   +1 more source

Dose of Bicarbonate to Maintain Plasma pH During Maximal Ergometer Rowing and Consequence for Plasma Volume

open access: yesFrontiers in Physiology, 2022
Rowing performance may be enhanced by attenuated metabolic acidosis following bicarbonate (BIC) supplementation. This study evaluated the dose of BIC needed to eliminate the decrease in plasma pH during maximal ergometer rowing and assessed the ...
Henning Bay Nielsen   +3 more
doaj   +1 more source

Clinical Characteristics of Patients with Methyl Alcohol Intoxication Followed up in the Intensive Care Unit and Factors Affecting Mortality

open access: yesBagcilar Medical Bulletin, 2023
Objective:Methyl alcohol is a solvent obtained by the fermentation of wood and used in various fields industrially. Due to its cheap and easy accessibility, it is frequently used to manufacture moonshine and can lead to severe morbidity and mortality ...
Kadir Arslan, Ayça Sultan Şahin
doaj   +1 more source

Veno-arterial extracorporeal membrane oxygenation as a bridge to recovery in acute aluminium phosphide poisoning: A case report

open access: yesAsian Journal of Medical Sciences, 2022
Aluminium phosphide (AlP) is a common fumigant used for controlling rodents and pests in grain storage facilities. Its consumption is reported in accidental or suicidal cases carrying high mortality.
Arvind Kumar   +4 more
doaj   +1 more source

[Lactic acidosis].

open access: yesMinerva medica, 1986
Lactic acidosis is a metabolic disturbance characterized by an increase of the production/clearance ratio of lactate. Lactate is a catabolite of glycolysis when this takes place under anaerobic conditions. Clinically LA is characterized by: signs of acidosis, venous blood lactate greater than 5 mMol/l, arterial pH less than 7.25.
MOLINATTI GM   +3 more
openaire   +5 more sources

Aging exaggerates blood pressure response to ischemic rhythmic handgrip exercise in humans

open access: yesPhysiological Reports, 2021
Ischemic skeletal muscle conditions are known to augment exercise‐induced increases in blood pressure (BP). Aging is also a factor that enhances the pressor response to exercise.
Daisuke Hasegawa   +10 more
doaj   +1 more source

Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]

open access: yes, 2010
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique   +7 more
core   +1 more source

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