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Wasting of lean tissue as a consequence of metabolic acidosis is a serious problem in patients with chronic renal failure. A possible contributor is inhibition by low pH of the System A (SNAT2) transporter, which carries the amino acid L-glutamine (L-Gln)
HA Varoqui (18249130) +8 more
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Metabolic Acidosis in Children: A Literature Review [PDF]
Metabolic acidosis is characterised by a primary decrease in the serum bicarbonate concentration, a secondary decrease in the arterial partial pressure of CO2, and a reduction in blood pH.
Preeti Shanbag, Syed Ahmed Zaki
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Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis [PDF]
Introduction: Acute metabolic acidosis of non-renal origin is usually a result of either lactic or ketoacidosis, both of which are associated with a high anion gap.
Treacher, David F +17 more
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Type B Lactic Acidosis in A Child with Relapsed non-Hodgkin Lymphoma [PDF]
Lactic acidosis is a major cause of metabolic acidosis in critically ill patients. Herein we report a child with relapsed non-Hodgkin’s lymphoma admitted to the pediatric intensive care unit (PICU) with profound lactic acidosis.
Gültaç Evren +5 more
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Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]
Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U. +5 more
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EEG Discontinuity and Neonatal Acidosis
The effect of acidosis on cerebral function was evaluated by computerized online EEG monitoring in 14 ventilated preterm infants less than 32 weeks’ gestation at the Department of Paediatrics and Neonatal Medicine, Royal Postgraduate Medical School ...
J Gordon Millichap
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Causes of metabolic acidosis in canine hemorrhagic shock : role of unmeasured ions [PDF]
Introduction: Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis ...
Faithfull, N. Simon +25 more
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Aim Exercise is able to increase both muscle protein synthesis and mitochondrial biogenesis. However, acidosis, which can occur in pathological states as well as during high‐intensity exercise, can decrease mitochondrial function, whilst its impact on ...
Amanda J. Genders +7 more
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Associations of severe hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral theraphy [PDF]
Includes bibliographical references (leaves 67-70).Severe symptomatic hyperlactataemia and lactic acidosis (SHLA) are life-threatening events that are occurring at increasing incidence levels in South Africa.
Osler, Meg
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The subject of acidosis in nephritis is one of such practical importance that it deserves emphasis from a clinical standpoint. Many significant observations bearing on this general topic have accumulated during the last ten years. In the study of this question, Van Slyke's simple method 1 of determining the alkali reserve of the body with the aid of ...
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