Results 31 to 40 of about 261,942 (260)

Two Extremely Low Birth Weight Infants Who Survived Functional Pulmonary Atresia with Normal Intracardiac Anatomy

American Journal of Perinatology Reports, 2019
For the first time, we report about two extremely low birth weight infants who were born at 25 and 22 weeks' gestation and who survived functional pulmonary atresia (fPA) with normal intracardiac anatomy. A slow, reflected, and bimodal blood flow pattern
Shuntaro Oka, Utako Kondo, Ayumi Oshima, Shun Matsumura, Masayo Kanai, Akio Ishiguro, Yoichi Iwamoto, Hirotaka Ishido, Isaku Omori, Satoshi Masutani   +9 more
doaj   +1 more source

Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney

Kidney & Blood Pressure Research, 2020
Introduction: The kidneys play a central role in eliminating metabolic waste products and drugs through transporter-mediated excretion along the proximal tubule.
Janine Gottier Nwafor, Marta Nowik, Naohiko Anzai, Hitoshi Endou, Carsten A. Wagner   +4 more
doaj   +1 more source

Impact of SARS-CoV-2 Infection on Unvaccinated Pregnant Women: Non-Reassuring Fetal Heart Rate Tracing Because of Placentitis

Viruses, 2023
In 2020, a new coronavirus, called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China. SARS-CoV-2 infection has been shown to be highly morbid in pregnant women, being a risk factor for several obstetric conditions leading to ...
Alexandra Claudet, Daniele De Luca, Elie Mosnino, Jérémie Mattern, Olivier Picone, Jeanne Sibiude, Estelle Wafo, Vassilis Tsatsaris, Emilie Giral, Irène Grefenstette, Julie Carrara, Dominique A. Badr, Marie-Hélène Saint-Frison, Sophie Prevot, Alexandra Benachi, Alexandre J. Vivanti   +15 more
doaj   +1 more source

An integrative analysis of cancer gene expression studies using Bayesian latent factor modeling

, 2010
We present an applied study in cancer genomics for integrating data and inferences from laboratory experiments on cancer cell lines with observational data obtained from human breast cancer studies.
Chen, Julia Ling-Yu, Chi, Jen-Tsan, Merl, Daniel, West, Mike   +3 more
core   +1 more source

Management of hyperkalemia in the acutely ill patient. [PDF]

, 2019
PURPOSE:To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients. METHODS:We searched MEDLINE and EMBASE for relevant papers published in English between Jan 1, 1938, and July 1,
Dépret, François, Legrand, Matthieu, Liu, Kathleen D, Peacock, W Frank, Rafique, Zubaid, Rossignol, Patrick   +5 more
core   +3 more sources

Extracellular Acidosis and mTOR Inhibition Drive the Differentiation of Human Monocyte-Derived Dendritic Cells

Cell Reports, 2020
Summary: During inflammation, recruited monocytes can differentiate either into macrophages or dendritic cells (DCs); however, little is known about the environmental factors that determine this cell fate decision. Low extracellular pH is a hallmark of a
Fernando Erra Díaz, Valeria Ochoa, Antonela Merlotti, Ezequiel Dantas, Ignacio Mazzitelli, Virginia Gonzalez Polo, Juan Sabatté, Sebastián Amigorena, Elodie Segura, Jorge Geffner   +9 more
doaj   +1 more source

Survival with Good Neurological Outcome despite Prolonged Cardiopulmonary Resuscitation and Extreme Acidosis after Out-of-Hospital Cardiac Arrest Due to Acute Myocardial Infarction: A Case Report and Review of the Literature

Clinics and Practice, 2023
We report the case of a 49-year-old male who suffered from a myocardial infarction with subsequent cardiac arrest. The emergency medical team began cardiopulmonary resuscitation, including defibrillation of ventricular fibrillation.
Sylvère Störmann, Kristina Busygina, Ralph Hein-Rothweiler, Julius Steffen, Stefanie Förderreuther, Nora Salein, Matthias W. Angstwurm   +6 more
doaj   +1 more source

Drug-induced metabolic acidosis [PDF]

, 2017
Summary: Drug causes of metabolic acidosis are numerous and their mechanisms are diverse. Broadly, they can cause metabolic acidosis with either a normal anion gap (e.g. drug-induced renal tubular acidosis) or an elevated anion gap (e.g.
Boton, Burdett, Burges, Dragovic, Fenves, Figge, Gerbaud, Hunter, Hussain, Kam, Karet, Knights, Kraut, Lee, Mirza, Oh, O’Connell, Peters, Porras, Reddi, Reyes, Robergs, Roscoe, Salpeter, Sawaya, Skinner, Soriano, Stewart, Tsao, Viollet, Walsh, Yombi, Yunos, Zamlauski-Tucker   +33 more
core   +1 more source

Increased cytoplasmic and nuclear S100A6 expression is associated with improved prognosis in ovarian cancer

BMC Cancer
Background Ovarian cancer is one of the most common gynaecological cancers affecting more than 300,000 women worldwide each year. S100 calcium-binding protein A6 (S100A6) is a member of the S100 family of calcium-binding proteins.
Aruba Farooq, Evren M. Akyuz, Brandon WQ Cheah, Suha Deen, Stewart G. Martin, Mattéa J. Finelli, Sarah Storr, Alan McIntyre   +7 more
doaj   +1 more source

L-DOS47 Elevates Pancreatic Cancer Tumor pH and Enhances Response to Immunotherapy

Biomedicines
Acidosis is an important immunosuppressive mechanism that leads to tumor growth. Therefore, we investigated the neutralization of tumor acidity to improve immunotherapy response. L-DOS47, a new targeted urease immunoconjugate designed to neutralize tumor
Bruna Victorasso Jardim-Perassi, Pietro Irrera, Oluwaseyi E. Oluwatola, Dominique Abrahams, Veronica C. Estrella, Bryce Ordway, Samantha R. Byrne, Andrew A. Ojeda, Christopher J. Whelan, Jongphil Kim, Matthew S. Beatty, Sultan Damgaci-Erturk, Dario Livio Longo, Kim J. Gaspar, Gabrielle M. Siegers, Barbara A. Centeno, Justin Y. C. Lau, Shari A. Pilon-Thomas, Arig Ibrahim-Hashim, Robert J. Gillies   +19 more
doaj   +1 more source