Results 31 to 40 of about 171,422 (307)

The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients

Frontiers in Molecular Biosciences
IntroductionCOVID-19 severity and high in-hospital mortality are often associated with severe hypoxemia, hyperlactatemia, and acidosis, yet the key players driving this association remain unclear.
Basma A. Yasseen, Aya A. Elkhodiry, Hajar El-sayed, Mona Zidan, Azza G. Kamel, Mohamed A. Badawy, Marwa S. Hamza, Riem M. El-Messiery, Mohamed El Ansary, Engy A. Abdel-Rahman, Engy A. Abdel-Rahman, Sameh S. Ali   +11 more
doaj   +1 more source

Two Extremely Low Birth Weight Infants Who Survived Functional Pulmonary Atresia with Normal Intracardiac Anatomy

American Journal of Perinatology Reports, 2019
For the first time, we report about two extremely low birth weight infants who were born at 25 and 22 weeks' gestation and who survived functional pulmonary atresia (fPA) with normal intracardiac anatomy. A slow, reflected, and bimodal blood flow pattern
Shuntaro Oka, Utako Kondo, Ayumi Oshima, Shun Matsumura, Masayo Kanai, Akio Ishiguro, Yoichi Iwamoto, Hirotaka Ishido, Isaku Omori, Satoshi Masutani   +9 more
doaj   +1 more source

Intoxicación por cianuro posterior a infusión prolongada de Nitroprusiato de sodio: a propósito de un caso

Medicina U.P.B., 2023
El nitroprusiato de sodio fue aprobado desde 1974 como medicamento para las crisis hipertensivas. Desde entonces existe controversia sobre el potencial tóxico del mismo.
Manuela Castaño Velez, Marie Claire Berrouet Mejía, Mateo Zuluaga Gómez   +2 more
doaj   +1 more source

Perspectivas atuais do tratamento da cetoacidose diabética em pediatria Current perspectives for treating children with diabetic ketoacidosis

Jornal de Pediatria, 2007
OBJETIVO: Revisar os conceitos atuais da fisiopatologia, diagnóstico e tratamento da cetoacidose diabética (CAD) na infância, assim como as medidas preventivas para evitar o edema cerebral. FONTES DOS DADOS: Os autores selecionaram artigos na MEDLINE com
Jefferson P. Piva, Mauro Czepielewski, Pedro Celiny R. Garcia, Denise Machado   +3 more
doaj   +1 more source

Characterization of acidosis in trauma patient

Journal of Emergencies, Trauma and Shock, 2020
Background: Recent data suggest that acidosis alone is not a good predictor of mortality in trauma patients. Little data are currently available regarding factors associated with survival in trauma patients presenting with acidosis.
Gregory S Corwin, Kevin W Sexton, William C Beck, John R Taylor, Avi Bhavaraju, Benjamin Davis, Mary K Kimbrough, Joseph C Jensen, Anna Privratsky, Rotnald D Robertson   +9 more
doaj   +1 more source

Distal renal tubular acidosis as a cause of osteomalacia in a patient with primary Sjögren's syndrome [PDF]

Vojnosanitetski Pregled, 2005
Background. One half of the patients with primary Sjögren’s syndrome has extraglandular manifestations, including renal involvement. The most frequent renal lesion is tubulo-interstitial nephritis, which manifests clinically as distal tubular acidosis ...
Jovelić Aleksandra, Stefanović Dušan
doaj   +1 more source

Cardiocongestive insufficiency due to vena cava thrombosis with secondary necro-exudative bronchopneumonia

Pubvet, 2021
The aim of this study was to report a case of vena cava thrombosis with secondary bronchopneumonia in a two-year-old Holsten breed cow from the municipality of Jacutinga, Rio Grande do Sul State, Brazil.
Maurijane Strapasson, Daniel Rossi, Júlia Fogilarini Moura, Juliana Franciele Ruzycki, Rodrigo Grando, Diorges Henrique Setim, Marina Menoncin Weschenfelder Rohenkohl, Mauro Antônio de Almeida, Geciane Toniazzo Backes, Daniela dos Santos de Oliveira   +9 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Increased cytoplasmic and nuclear S100A6 expression is associated with improved prognosis in ovarian cancer

BMC Cancer
Background Ovarian cancer is one of the most common gynaecological cancers affecting more than 300,000 women worldwide each year. S100 calcium-binding protein A6 (S100A6) is a member of the S100 family of calcium-binding proteins.
Aruba Farooq, Evren M. Akyuz, Brandon WQ Cheah, Suha Deen, Stewart G. Martin, Mattéa J. Finelli, Sarah Storr, Alan McIntyre   +7 more
doaj   +1 more source

L-DOS47 Elevates Pancreatic Cancer Tumor pH and Enhances Response to Immunotherapy

Biomedicines
Acidosis is an important immunosuppressive mechanism that leads to tumor growth. Therefore, we investigated the neutralization of tumor acidity to improve immunotherapy response. L-DOS47, a new targeted urease immunoconjugate designed to neutralize tumor
Bruna Victorasso Jardim-Perassi, Pietro Irrera, Oluwaseyi E. Oluwatola, Dominique Abrahams, Veronica C. Estrella, Bryce Ordway, Samantha R. Byrne, Andrew A. Ojeda, Christopher J. Whelan, Jongphil Kim, Matthew S. Beatty, Sultan Damgaci-Erturk, Dario Livio Longo, Kim J. Gaspar, Gabrielle M. Siegers, Barbara A. Centeno, Justin Y. C. Lau, Shari A. Pilon-Thomas, Arig Ibrahim-Hashim, Robert J. Gillies   +19 more
doaj   +1 more source