The role of carbonic anhydrase IX in cancer development: links to hypoxia, acidosis, and beyond
Cancer Metastasis Review, 2019 Cancer development is a complex process that follows an intricate scenario with a dynamic interplay of selective and adaptive steps and an extensive cast of molecules and signaling pathways.
S. Pastoreková, R. Gillies
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Ruminal acidosis, bacterial changes, and lipopolysaccharides.
Journal of Animal Science, 2020 Acute and subacute ruminal acidosis (SARA) are common nutritional problems in both beef and dairy cattle. Therefore, the objective of this review is to describe how ruminal Gram-negative bacteria could contribute to the pathogenesis of ruminal acidosis ...
H. Monteiro, A. Faciola
semanticscholar +1 more source
Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]
, 1990 Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U. +5 more
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Cochlear Implantation in Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes Syndrome: Case Presentation [PDF]
, 2022 Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes syndrome is a multisystem, progressive neurodegenerative condition, and the most common mitochondrial cytopathy.
Manohar Bance +5 more
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HMG-CoA Lyase Deficiency: A Retrospective Study of 62 Saudi Patients
Frontiers in Genetics, 2022 3-Hydroxy-3-methylglutaryl-coenzyme A lyase deficiency (HMG-CoA lyase) is a rare inborn error of leucine degradation and ketone body synthesis, caused by homozygous or compound heterozygous disease-causing variants in HMGCL.
Majid Alfadhel +15 more
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Journal of Clinical Sciences, 2020 Background: Estimation of the serum pH and base excess as determinants of the adequacy of resuscitation may predict the patient outcome in peritonitis. Materials, Patients and Methods: This was a prospective study conducted in University College Hospital,
O Oludolapo Afuwape +2 more
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Causes, Consequences, and Therapy of Tumors Acidosis
Cancer Metastasis Review, 2019 While cancer is commonly described as “a disease of the genes,” it is also associated with massive metabolic reprogramming that is now accepted as a disease “Hallmark.” This programming is complex and often involves metabolic cooperativity between cancer
S. Pillai +5 more
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Causes of metabolic acidosis in canine hemorrhagic shock : role of unmeasured ions [PDF]
, 2007 Introduction: Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis ...
Faithfull, N. Simon +25 more
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EEG Discontinuity and Neonatal Acidosis
Pediatric Neurology Briefs, 1994 The effect of acidosis on cerebral function was evaluated by computerized online EEG monitoring in 14 ventilated preterm infants less than 32 weeks’ gestation at the Department of Paediatrics and Neonatal Medicine, Royal Postgraduate Medical School ...
J Gordon Millichap
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Risk factors for lactic acidosis and severe hyperlactataemia in HIV-1-infected adults exposed to antiretroviral therapy. [PDF]
, 2007 BACKGROUND: Severe hyperlactataemia and lactic acidosis are rare serious complications of antiretroviral therapy (ART). METHODS: Lactic acidosis was defined as pH 5 mmol/l.
Lactic Acidosis International Study Group
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