Cardiac pH-Imaging With Hyperpolarized MRI
Frontiers in Cardiovascular Medicine, 2020 Regardless of the importance of acid-base disturbances in cardiac disease, there are currently no methods for clinical detection of pH in the heart. Several magnetic resonance imaging techniques hold translational promise and may enable in-vivo mapping ...
Nikolaj Bøgh +5 more
doaj +1 more source
Acid-base homeostasis in the human system [PDF]
Acid-base regulation is a cooperative phenomena in vivo with body fluids, extracellular and intracellular buffers, lungs, and kidneys all playing important roles.
White, R. J.
core +1 more source
Modelling of non-steady-state concentration profiles at ISFET-based coulometric sensor—actuator systems [PDF]
, 1990 Acid or base concentrations can be determined very rapidly by performing an acid—base titration with coulometrically generated OH− or H+ ions at a noble metal actuator electrode in close proximity to the pH-sensitive gate of an ion-sensitive field effect
Bergveld, P. +5 more
core +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Learning in constructivist environments: a research based on the acid-base subject [PDF]
Investigações em Ensino de Ciências, 2004 This communication intends to show as a constructivist environment permits a better learning of some concepts related to the acid-base subject, where generally students have some misconceptions at the beginning, as many researches had proved.
Vera Gouveia, Jorge Valadares
doaj
Mixing characterization inside microdroplets engineered on a microcoalescer [PDF]
, 2007 We use a microdevice where microdroplets of reagents are generated and coalesce in a carrier continuous phase. The work focuses on the characterization of the mixing step inside the droplets, in the perspective to use them for chemical kinetic data ...
Cristobal, Galder +5 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Pemanfaatan Ekstrak Tanaman Ketan Hitam (Oryza Sativa Glutinosa) sebagai Indikator Asam Basa [PDF]
, 2016 Research was conducted with the aims to determine pH range, percentage acid base indicator titration error, and stability of Oryza sativa Glutinosa extract as acid base indicator. Oryza sativa Glutinosa grains respectively extracted with maseration using
Amran, E. Y. (Elva) +2 more
core
Associations between Dietary Acid Load and Biomarkers of Inflammation and Hyperglycemia in Breast Cancer Survivors. [PDF]
, 2019 Metabolic acidosis can lead to inflammation, tissue damage, and cancer metastasis. Dietary acid load contributes to metabolic acidosis if endogenous acid-base balance is not properly regulated.
Hollenbach, Kathryn +5 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source