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Electrolytes: Acid–base balance
Maintenance of acid-base balance is fundamental for the normal function of biological processes, mainly due the pH dependence of enzyme function.
P.B. Mark, K.K. Stevens, A.G. Jardine
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To ensure normal body function, specific pH levels need to be maintained. In average it is about 7.4 (◘ Table 22.1). The pH level reflects the effective H+-ion concentration or H+-ion activity. Increase of H+-ions and decrease of OH−-ions result in a shift of the pH level towards the acid range and vice versa to the alkaline range (H+-ions = acid ions;
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Stewart and beyond: New models of acid-base balance
Stewart and beyond: New models of acid-base balance. The Henderson-Hasselbalch equation and the base excess have been used traditionally to describe the acid-base balance of the blood. In 1981, Stewart proposed a new model of acid-base balance based upon
Howard E Corey
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The Kidney in Acid-Base Balance
Pediatric Clinics of North America, 1995The practitioner's approach to the pediatric patient with metabolic acidosis begins with calculation of the serum anion gap, which allows the clinician to place the patient in one of two categories of acid-base disturbance: a normal anion gap acidosis or high anion gap acidosis.
J D, Hanna, J I, Scheinman, J C, Chan
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Disorders of Acid-Base Balance
Pediatric Clinics of North America, 1990Acid-base disorders are common in sick children. This article is a practical guide to the differential diagnosis and treatment of simple and mixed acid-base disorders of children. Special attention is given to fundamentals of acid-base physiology, to clinical use of the Henderson equation, and to interpretation of readily available laboratory tests.
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ELECTROLYTES AND ACID-BASE BALANCE IN HYPOTHERMIA
Survey of Anesthesiology, 1956Dogs were cooled in an ice-water bath, and plasma electrolytes were measured at heart temperatures of 38°C, 28°C and 25°C. A ‘cold acidosis’ occurred during hypothermia that is attributable largely to temperature-influenced physico-chemical factors related to the buffer systems.
D R, AXELROD, D E, BASS
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Acid-base balance in heart failure
Journal of Nephrology, 2006Abstract: In end-stage heart failure, various acid-base disorders can be discovered due to the renal loss of hydrogenions and hydrogen ion movements into cells, the reduction of the effective circulating volume, hypoxemia and renal failure. This justifies the occurrence of metabolic alkalosis, metabolic acidosis, respiratory alkalosis,
FRANGIOSA A +3 more
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The Kidney in Acid-Base Balance
Archives of Internal Medicine, 1965Introduction SUDDEN CHANGES in body acid-base balance are neutralized by the blood buffers within seconds. The lungs partially compensate for acidosis or alkalosis through increased or decreased excretion of CO2in a matter of minutes. The kidneys, however, are ultimately responsible for maintaining body pH within narrow limits.
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Disorders of acid-base balance
Critical Care Medicine, 2007Intensivists spend much of their time managing problems related to fluids, electrolytes, and blood pH. Recent advances in the understanding of acid-base physiology have resulted from the application of basic physical-chemical principles of aqueous solutions to blood plasma.
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The American Journal of Nursing, 1975
the chemical reactions of body fluids become too acid or too alkaline. An acid, a substance that contains hydrogen ions that can be given off or donated to other substances, is called a proton donor. A base can receive a hydrogen ion and is a proton acceptor.
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the chemical reactions of body fluids become too acid or too alkaline. An acid, a substance that contains hydrogen ions that can be given off or donated to other substances, is called a proton donor. A base can receive a hydrogen ion and is a proton acceptor.
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