Results 131 to 140 of about 41,896 (210)

Acid-sensing ion channel 1a exacerbates renal ischemia-reperfusion injury through the NF-κB/NLRP3 inflammasome pathway. [PDF]

J Mol Med (Berl), 2023
Yang Y, Jin S, Zhang J, Chen W, Lu Y, Chen J, Yan Z, Shen B, Ning Y, Shi Y, Chen J, Wang J, Xu S, Jia P, Teng J, Fang Y, Song N, Ding X.   +17 more
europepmc   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Mechanism of acid-sensing ion channel modulation by Hi1a. [PDF]

J Gen Physiol
Berger KD, MacLean DM.
europepmc   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

The acid-sensing ion channel 1a modulates anxiety- and depression-related behaviors via its influencing on the activity of corticotropin-releasing hormone-expressing neurons in the hypothalamic paraventricular nucleus in male mice. [PDF]

Transl Psychiatry
Yue J, Zhang Q, Wang M, Yao X, Wang M, Liu L, Huang Z, Xing Y, Yan J, Yan Z, Song XL, Wang W.   +11 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

The relationship between acid-sensing ion channel, ASIC2, and oncogenic β-catenin signaling in ovarian cancer. [PDF]

Sci Rep
Joshi T, Chokshi S, Wilhite A, Singleton MH, Catranis E, Scalici J, Lee KJ.   +6 more
europepmc   +1 more source

Characteristics of acid-sensing ion channel currents in male rat muscle dorsal root ganglion neurons following ischemia/reperfusion. [PDF]

Physiol Rep, 2023
Li Q, Qin L, Li J.
europepmc   +1 more source

Multicomponent Peptide‐MXene‐Hyaluronic Acid Hydrogel as a Conductive Scaffold for Enhanced Fibroblast Proliferation and Migration Under Electrical Stimulation

Advanced Healthcare Materials, EarlyView.
An electrically conductive FmocFF/MXene/hyaluronic acid hydrogel combines extracellular matrix‐like architecture, self‐healing behavior, oxidation‐resistant conductivity, and biochemical cues in a single scaffold. By enabling physiologically relevant electrical stimulation, the platform enhances fibroblast attachment, proliferation, and migration ...
Offir Loboda, Dana Cohen‐Gerassi, Dor Aaron Goldstein, Or Messer, Bar Favelukis, Ehud Gazit, Maxim Sokol, Lihi Adler‐Abramovich   +7 more
wiley   +1 more source

Molecular Insights into Single-Chain Lipid Modulation of Acid-Sensing Ion Channel 3. [PDF]

J Phys Chem B
Bandarupalli R, Roth R, Klipp RC, Bankston JR, Li J.   +4 more
europepmc   +1 more source