Results 41 to 50 of about 6,551,457 (314)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Overcoming thermostability challenges in mRNA–lipid nanoparticle systems with piperidine-based ionizable lipids

Communications Biology
Lipid nanoparticles (LNPs) have emerged as promising platforms for efficient in vivo mRNA delivery owing to advancements in ionizable lipids. However, maintaining the thermostability of mRNA/LNP systems remains challenging. While the importance of only a
Kazuki Hashiba, Masamitsu Taguchi, Sachiko Sakamoto, Ayaka Otsu, Yoshiki Maeda, Hirofumi Ebe, Arimichi Okazaki, Hideyoshi Harashima, Yusuke Sato   +8 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. [PDF]

, 2006
Stearoyl-CoA desaturase (SCD) is a key enzyme that determines the composition and metabolic fate of ingested fatty acids, in particular the conversion of trans-vaccenic acid (TVA) to conjugated linoleic acid (CLA).
Renaville, B, Mullen, Anne, Anne Mullen, Moloney, F, RENAVILLE, Benedicte France Ghislaine, MOLONEY F, LARONDELLE Y, Helen M. Roche, Molonay, Fiona, Roche, HM, Fiona Moloney, Yvan Larondelle, Mullen, A, Renaville Bénédicte, Moloney, Fiona, Larondelle, Yvan, Yves-Jacques Schneider, MULLEN A, SCHNEIDER YJ ROCHE HM, Roche, Hélèje M., Renaville, Bénédicte, Roche, Helen M, Larondelle, Y, Schneider, Yves-Jacques   +23 more
core   +1 more source

Randomized Trial of Dietary Acid Reduction and Acid-Base Status of Patients With CKD and Normal Estimated GFR

Kidney International Reports
Introduction: Modern acid-producing diets in patients with stage G3 to G5 chronic kidney disease (CKD) can cause severe acid accumulation with metabolic acidosis and less severe accumulation causing eubicarbonatemic acidosis in stages G2 to G3, each with
Nimrit Goraya, Nicolaos E. Madias, Jan Simoni, Maninder Kahlon, Nazan Aksan, Donald E. Wesson   +5 more
doaj   +1 more source

Prevalence of Dengue, Chikungunya and Zika Viruses in Blood Donors in the State of Pará, Northern Brazil: 2018–2020

Medicina, 2022
Arboviruses have been reported over the years as constant threats to blood transfusion recipients, given the high occurrence of asymptomatic cases and the fact that the presence of viremia precedes the onset of symptoms, making it possible that infected ...
Leticia Martins Lamarão, Angelita Silva Miranda Corrêa, Renata Bezerra Hermes de Castro, Carlos Eduardo de Melo Amaral, Patricia Danin Jordão Monteiro, Mauricio Koury Palmeira, Luane Nascimento Lopes, Angela Neves Oliveira, Maria Salete Maciel de Lima, Caroline Aquino Moreira-Nunes, Rommel Rodríguez Burbano   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Effects of different saliva pH on hybrid composite resin surface roughness

Dental Journal, 2011
Background: Currently, hybrid composite resin is the mostly used filling material to restore esthetic and function. During function, this material is in contact with various pH from food consumption, which is acidic and alkali which may effect the ...
Nirawati Pribadi, Adioro Soetojo
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

METAL OF IRON (Fe) AND MANGAN (Mn) FROM WASTE WATER COAL MINING WITH FITOREMEDIATION TECHNIQUES WITH USING FLOATING FERN (Salvinia natans), WATER LETTUCE (Pistia stratiotes) AND WATER-HYACINTH (Eichornia crassipes)

Biovalentia: Biological Research Journal, 2018
Coal mining activities can cause problems from for environment, especially the mining with surface mining method producing acid mine water. To solve these problems, we need to restore the output water conditionbefore it flows into the public waters so it
Mardalena Mardalena, Muhammad Faizal, A Napoleon   +2 more
doaj   +1 more source