Results 61 to 70 of about 6,551,457 (314)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Amperometric biosensor for formic acid in air [PDF]

open access: yes, 2000
The possibility of developing a simple, inexpensive and specific personal passive ”real-time” air sampler based on biosensor technology was investigated. Formic acid was used as a model substance.
Turner, Anthony P. F.   +14 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Metabolomics of dietary fatty acid restriction in patients with phenylketonuria [PDF]

open access: yes, 2012
Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA).
Berthold Koletzko (144194)   +39 more
core   +1 more source

Application of biostimulant and CaO to remediate acid mine drainage on the coal mining land in Lampung Sumatra Island

open access: yesJournal of Degraded and Mining Lands Management, 2018
Mining using an open pit system may lead to a deterioration in the quality of the environment in term of the extent of the cleared land, heavy metals contamination on the overburden rock, the formation of acid mine drainage (AMD) with a pH
Mohammad Nurcholis   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

EFFECT OF HUMIC ACID AND SALICYLIC ACID ON THE GROWTH, YIELD AND QUALITY IN ONION [PDF]

open access: yes, 2021
A Thesis Submitted to the Faculty of Agriculture, Sher-e-Bangla Agricultural University, Dhaka, In Partial fulfillment of the requirements for the degree of MASTER OF SCIENCE IN HORTICULTUREThe field experiment was conducted at the ...
Nahar, Khairun
core  

“Acid + Oxidant” Treatment Enables Selective Extraction of Lithium from Spent NCM523 Positive Electrode

open access: yesBatteries
With the rapid development of new energy vehicles and energy storage industries, the demand for lithium-ion batteries has surged, and the number of spent LIBs has also increased. Therefore, a new method for lithium selective extraction from spent lithium-
Hui Wang   +5 more
doaj   +1 more source

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