Results 71 to 80 of about 4,637,980 (251)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

High-throughput analysis of total plasma fatty acid composition with direct in situ transesterification. [PDF]

, 2010
Plasma fatty acid (FA) composition reflects dietary intake and endogenous turnover and is associated with health outcomes on a short and long term basis. The total plasma FA pool represents the composition of all FA containing lipid fractions.
Hans Demmelmair, Demmelmair Hans, Koletzko Berthold, Glaser, Claudia, Berthold Koletzko, Koletzko, Berthold, Glaser Claudia, Demmelmair, Hans, Claudia Glaser   +8 more
core   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Direct extraction of oil from sunflower seeds by twin-screw extruder according to an aqueous extraction process: Feasibility study and influence of operating conditions [PDF]

, 2007
The objective of this study was to evaluate the feasibility of an aqueous process to extract sunflower seed oil using a co-rotating twin-screw extruder. Aqueous extraction was carried out using whole seeds and the influence of the operating conditions on
Evon, Philippe, Pontalier, Pierre Yves, Ph. Evon, V. Vandenbossche, P.Y. Pontalier, Pontalier, Pierre-Yves, L. Rigal, Vandenbossche, Virginie, Rigal, Luc   +8 more
core   +1 more source

Investigation on Walnut Kernel Oil Extraction Using Different Methods

BioResources, 2022
Extraction of oil from walnut kernel as raw material was explored using the method of pressing. Soxhlet and ultrasonic-assisted extractions of walnut oil, its evaluation index, the extraction process optimization by single factor experiment, the physical
Jingwen Wang, Kai Zhang, Jian Sheng, Hao Ren, Juntao Gong, Yan Wang, Dongyu Pan, Ximing Wang, Yinan Hao   +8 more
doaj   +2 more sources

Mineral Acid Co-Extraction in Reactive Extraction of Lactic Acid Using a Thymol-Menthol Deep Eutectic Solvent as a Green Modifier

Molecules
Carboxylic acids can be isolated from fermentation broths using reactive liquid-liquid extraction, offering an alternative to the environmentally harmful state-of-the-art process of precipitating calcium lactate.
Paul Demmelmayer, Marija Ćosić, Marlene Kienberger   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Novel Caffeine-Assisted Aqueous Extraction Strategy for Enhanced Solubilization of Polycyclic Aromatic Hydrocarbons from Creosote-Treated Waste Wood

Molecules
This study evaluates caffeine-assisted aqueous extraction systems for the enhanced extraction of Σ16 US EPA priority polycyclic aromatic hydrocarbons (PAHs) from waste creosote-infused wood.
Željka M. Nikolić, Nebojša R. Radović, Aleksandra M. Radulović, Milica P. Marčeta Kaninski, Vladimir M. Nikolić, Dragana Z. Živojinović   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

[Tooth extraction under medication with acetylsalicylic acid.] [PDF]

, 2006
PURPOSE: The purpose of this prospective study was to show and analyze the bleeding complications after teeth extraction under therapy with 100 mg acetylsalicylic acid (ASA) and to compare them to bleeding complications after teeth extraction in patients
Hemelik, M, Kessler, B, Wahl, G
core   +2 more sources