Results 91 to 100 of about 445,203 (313)
pH Sensitive Anticancer Prodrug: Amide of Kemp's Acid
, 2009 Solid tumours are characterised by lower extracellular pH (as low as 5.8 pH) compared to normal healthy cellular pH (actively regulated at pH 7.3). This difference may be exploited with an acid-sensitive anti-tumour prodrug which releases a cytotoxin ...
Brooks, Robert Turongo
core
The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]
, 2008 Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page +3 more
core +1 more source
Receptor‐Free Identification of Toxic Gases Enabled by Hygroscopic Aqueous Salt Films
Advanced Functional Materials, EarlyView.Water as a gas sensor coating sounds impossible—until it stops evaporating. Here, hygroscopic salt solutions (LiCl, LiBr, H3PO4) form non‐drying aqueous films on CNT chemiresistors under ambient air. Gases partition into these liquid layers, sometimes transforming into water, and generate salt‐specific resistance fingerprints across a four‐channel ...
Seongwoo Lee +5 more
wiley +1 more source
High aspect ratio nanocellulose from an extremophile spinifex grass by controlled acid hydrolysis [PDF]
, 2017 During the last two decades, work surrounding the preparation of a vast array of cellulose nanomaterials from both wood and non-wood based sources has steadily intensified.
Garvey, Christopher J. +5 more
core +1 more source
Advanced Functional Materials, EarlyView.A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe,
Minseong Chae +27 more
wiley +1 more source
Hydrolysis of corn stover pretreated by DESs with carbon-based solid acid catalyst
SN Applied Sciences, 2020 This study evaluated two hydrolysis strategies that involve a two-step and a one-pot process for the hydrolysis of cellulose. The two-step process consisted of cellulose pretreatment with deep eutectic solvent, followed by hydrolysis promoted by the ...
Shuanglan Hu +4 more
doaj +1 more source
Studies Towards a pH-Sensitive Anticancer Prodrug Model
, 2010 Tumour-activated prodrug (TAP) is designed to aim at increasing the prodrug selectivity to kill cancer cells. One strategy to is to design a TAP containing an amine cytotoxin, present as an amide function, which could be released more rapidly in the low ...
Teng, Xiao Shi
core
, 2016 A major challenge that must be overcome for the commercial production of levulinic acid from lignocellulosics is to reduce equipment blockage and corrosion.
Doherty, William O.S. +3 more
core +1 more source
Storage oil hydrolysis during early seedling growth [PDF]
, 2009 Storage oil breakdown plays an important role in the life cycle of many plants by providing the carbon skeletons that support seedling growth immediately following germination.
Eastmond, Peter J., Quettier, Anne-Laure
core +1 more source
Advanced Functional Materials, EarlyView.An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández +14 more
wiley +1 more source