Results 51 to 60 of about 786,299 (308)
Kinetic proofreading at single molecular level: Aminoacylation of tRNA^{Ile} and the role of water as an editor [PDF]
, 2013 Proofreading/editing in protein synthesis is essential for accurate translation of information from the genetic code. In this article we present a theoretical investigation of efficiency of a kinetic proofreading mechanism that employs hydrolysis of the ...
Bagchi, Biman, Santra, Mantu
core +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
International Journal of Recycling of Organic Waste in AgriculturePurpose In Saudi Arabia, owing to the abundant livestock, manures are a source of commercial humic amendments. Climate (hot weather plus scarcity of water sources) makes composting very difficult and compulsory to obtain these humic amendments without ...
Carla Bellera +3 more
doaj +1 more source
Cellulose Nanocrystal Isolation from Hardwood Pulp using Various Hydrolysis Conditions
Molecules, 2019 To expand the application field of the pulping industry, this study conducted a series of sample preparations for processing cellulose nanocrystals (CNCs) from a dry hardwood pulp to achieve optimal sulfuric acid hydrolysis.
Kuan-Hsuan Lin +2 more
doaj +1 more source
A procedure for the determination of proteolytic activity [PDF]
, 1950 The difficulties introduced by the desire to maintain a constant pH during an enzyme-catalyzed hydrolysis of peptide-like substrates and at the same time to determine the extent of hydrolysis by an acid-base titration have been pointed out (1), but to ...
Iselin, Beat M., Niemann, Carl
core
Multifunctional star-shaped polylactic acid implants for use in angioplasty [PDF]
, 2014 Star-shaped polylactic acids with different tacticity were synthesized and both polymers are capable of bestowing properties of anticoagulation and angiogenesis to their living host.
Kiran, M. S. +3 more
core +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Utilization of whole sorghum crop residues for bioethanol production [PDF]
, 2016 Sorghum is the fifth most important cereal worldwide and is a major source of agricultural residues in tropical regions. Bioconversion of whole sorghum crop residues comprising stalks, leaves, peduncles and panicles to ethanol has great potential for ...
Agu, Reginald +3 more
core +3 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Applied Sciences, 2020 Wheat straw is an easily affordable, cost-effective and natural source of antioxidants and cellulose, but its full potential is not yet utilized. In the present investigation, an auto-hydrolytic process was applied to recover both antioxidant phenolic ...
Andrea Bassani +4 more
doaj +1 more source