Results 61 to 70 of about 445,203 (313)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Enzymic Hydrolysis of Colanic Acid [PDF]

open access: yesEuropean Journal of Biochemistry, 1971
The isolation of of oligosaccharides produced by the action of phage-inducee enzymes on the bacterial exopolysaccharide colanic acid is reported. The products from colanic acid produced by different strains of Escherichia coli and Salmonella typhimurium were hexasaccharides which differed in their acyl substituents.
openaire   +2 more sources

Pretreatment of wheat straw by nonionic surfactant-assisted dilute acid for enhancing enzymatic hydrolysis and ethanol production

open access: yes, 2010
Pretreating wheat straw (WS) with combined use of varied sulfuric acid concentration (0-3%, w/v) and Tween 20 concentration (0-1%) was investigated in an attempt to enhance the hydrolysis and fermentability of pretreated WS. Enzymatic hydrolysis yield of
Wan, YH   +3 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Effect of enzymatic hydrolysis process on flavor compounds of Lentinula edodes

open access: yesShipin yu jixie
ObjectiveTo study the effect of the enzymatic hydrolysis process on the flavor compounds of Lentinula edodes.MethodsThe optimized enzymatic hydrolysis process is adopted, with free amino acid, 5'-nucleotide, equivalent umami concentration (EUC), volatile
CUI Guomei   +6 more
doaj   +1 more source

Effect of chemical steeping on yields of glucose and xylose from dilute acid hydrolysis of extract from oil palm trunk

open access: yes, 2021
The effectiveness of chemical steeping was examined as a novel pretreatment prior to hydrolysis to influence the extractable yield of glucose and xylose from oil palm trunk (OPT).
Wong, Lih Jiun   +4 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Implementation of Auto-Hydrolysis Process for the Recovery of Antioxidants and Cellulose from Wheat Straw

open access: yesApplied Sciences, 2020
Wheat straw is an easily affordable, cost-effective and natural source of antioxidants and cellulose, but its full potential is not yet utilized. In the present investigation, an auto-hydrolytic process was applied to recover both antioxidant phenolic ...
Andrea Bassani   +4 more
doaj   +1 more source

Vitamin B2 content determination in liver paste by using acid and acid-enzyme hydrolysis [PDF]

open access: yesVojnosanitetski Pregled, 2007
Background/Aim. Vitamin B2 is available in foodstuff in the form of coenzyme and in free form. For its content determination a few procedures should be performed (deliberation from a complex, extraction of free and deliberated form) and detection ...
Basić Zorica   +2 more
doaj   +1 more source

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