Results 31 to 40 of about 2,907,636 (184)

Minocycline-associated rimmed vacuolar myopathy in a patient with rheumatoid arthritis

BMC Neurology, 2012
Background The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle specimens.
Bokuda Kota, Sugaya Keizo, Tamura Shunichiro, Miyamoto Kazuhito, Matsubara Shiro, Komori Takashi   +5 more
doaj   +1 more source

Amylosucrase as a Versatile Biocatalyst for Next‐Generation Functional Ingredients: Starch Modification and Glycoside Synthesis

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Amylosucrase (ASase, E.C. 2.4.1.4) is a transglucosidase that catalyzes α‐glucan synthesis and transglycosylation reactions using sucrose as the sole substrate. Unlike Leloir glycosyltransferases requiring expensive nucleotide sugars, ASases utilize readily available sucrose as a cost‐effective glucose donor, offering economic advantages for ...
Dong‐Ho Seo, Byung‐Hoo Lee, Sang‐Ho Yoo   +2 more
wiley   +1 more source

Ureteroscopic Removal of Left Ureteral Lithiasis in a Patient with Acid Maltase Deficiency Disease

, 1993
Acid maltase deficiency is a rare cause of respiratory insufficiency (1). Clinical and biochemical manifestations of the disease arise from a deficiency of the lysosomal enzyme α1,4−glucosidase (acid maltase) which degrades glycogen to free glucose (2 ...
Grogono, Alan, Garth, Kevin, Gitlin, Melvin, Jahr, Jonathan   +3 more
core   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, Volume 13, Issue 47, 24 August 2026.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Adult onset acid maltase deficiency

, 2003
Glikojen depo hastalığı tip II (GDHII, Pompe hastalığı), lizozomal alfa-glukosidaz eksikliğine bağlı otosomal resesif bir, hastalıktır, infantil, juvenil ve adult olmak üzere üç farklı form tanımlanmıştır.
Yakup Sarıca, Suzan Zorludemir, Filiz Koç   +2 more
core   +1 more source

Abalone Gut Microbiome Regulators: A Review Synthesizing Gut Physiology, Microorganisms, Diet and the Environment

Aquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT Abalone are economically, ecologically and culturally significant marine molluscs, with both wild and farmed populations under pressure due to intrinsic and extrinsic stressors. Abalone performance and health are centred on a highly specialized digestive system supported by a diverse gut microbiome, which enables nutrient assimilation ...
Jinchen Guo, Leonie Venter, Donnabella C. Lacap‐Bugler, Andrea C. Alfaro   +3 more
wiley   +1 more source

Acid maltase levels in muscle in heterozygous acid maltase deficiency and in non-weak and neuromuscular disease controls [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1970
Acid maltase (AM) deficiency carriers can be detected by muscle enzyme assay. The assay indicates that, just as in infantile and childhood cases, adult cases of the disease are transmitted by autosomal recessive inheritance. With the maltose hydrolysis assay, in some neuromuscular diseases, muscle AM activity can be as low as in heterozygous AM ...
A G, Engel, M R, Gomez
openaire   +2 more sources

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

Small, Volume 22, Issue 43, 3 August 2026.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Prevalence and risk factors for vitamin C deficiency in North and South India: A two centre population based study in people aged 60 years and over [PDF]

, 2011
BackgroundStudies from the UK and North America have reported vitamin C deficiency in around 1 in 5 men and 1 in 9 women in low income groups. There are few data on vitamin C deficiency in resource poor countries.ObjectivesTo investigate the prevalence ...
K. Gupta Sanjeev, Maraini Giovanni, Ravilla D. Ravindran, Giovanni Maraini, Ravilla Thulasiraj D., John Neena, Thulasiraj D. Ravilla, John, Neena, Thulasiraj D Ravilla, Young, Ian S., R Jayanthi, S. Young Ian, Usha Chakravarthy, Chakravarthy Usha, Fletcher Astrid E., Young, Ian S, Ravilla D Ravindran, Praveen Vashist, Ravilla, Thulasiraj D, Chakravarthy, Usha, Kathryn E. Fitzpatrick, Fitzpatrick, Kathryn E, Camparini, Monica, Astrid E Fletcher, Gupta, S.K., R. Jayanthi, Maraini, G., John, N., Ravilla, T.D., Fitzpatrick Kathryn E., Fitzpatrick, K.E., Maraini, Giovanni, Camparini, M., Fletcher, Astrid E, Gupta, Sanjeev K, Monica Camparini, Kathryn E Fitzpatrick, Ravindran, Ravilla D, Neena John, Fletcher, A.E., Jayanthi, R, Sanjeev K Gupta, Ravindran, R.D., Vashist Praveen, Sanjeev K. Gupta, Vashist, Praveen, Astrid E. Fletcher, Camparini Monica, Ian S Young, Jayanthi R., Jayanthi, R., Ravindran Ravilla D., Vashist, P., Ian S. Young   +53 more
core   +2 more sources

Chronic, but not acute, treatment with GLP‐2 and GIP in combination increases glucose absorption in the isolated vascularly perfused rat intestine

Physiological Reports, Volume 14, Issue 16, August 2026.
Chronic GLP‐2 + GIP treatment increases glucose absorption. Abstract The gut hormones, glucagon‐like peptide‐2 (GLP‐2) and glucose‐dependent insulinotropic polypeptide (GIP), may be important regulators of intestinal nutrient absorption. Using the isolated vascularly perfused rat intestine of male rats, we investigated the chronic and subacute ...
Katrine D. Galsgaard, Tyler A. Cookson, Ida M. Modvig, Valentina Abba, Samuel A. J. Trammell, Mette M. Rosenkilde, Lærke S. Gasbjerg, Charlotte M. Sørensen, Bolette Hartmann, Jens J. Holst   +9 more
wiley   +1 more source