Results 181 to 190 of about 541,119 (315)

ASSOCIATION OF ACID AND ALKALINE PHOSPHATASE AMONG THE THYROID PATIENTS

, 2013
Thyroidism is becoming one of the most prevalent diseases due to the malfunctioning of the thyroid gland. The objective of the present study is to observe the association of acid phosphatase and alkaline phosphatase with thyroid disorder.
PRATHYUSHA, U., B.DHARANI PRIYA
core  

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Thermotolerant class A acid phosphatase active across broad pH range and diverse substrates. [PDF]

Protein Sci
Recio MI, Gavira JA, de La Torre J, Cano-Muñoz M, Martínez-Rodriguez S, Daddaoua A, Duque E, Ramos JL.   +7 more
europepmc   +1 more source

Allelic Variation in GmPAP14 Alters Gene Expression to Affect Acid Phosphatase Activity in Soybean. [PDF]

Int J Mol Sci, 2023
Kong Y, Liu Y, Li W, Du H, Li X, Zhang C.   +5 more
europepmc   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Machine Learning- and AI-Driven QSAR Models for the Discovery of Novel Potential Fungicides: FAPI (Fungicide Targeting Acid Phosphatase Inhibition). [PDF]

J Agric Food Chem
Gálvez-Llompart M, Zanni R, Morales Y, Polonio Á, Fernández-Ortuño D, Pérez-García A, Pérez-Giménez F.   +6 more
europepmc   +1 more source

Identification and Functional Analysis of Tartrate-Resistant Acid Phosphatase Type 5b (TRAP5b) in Oreochromis niloticus. [PDF]

Int J Mol Sci, 2023
Lei Y, Fu S, Yang Y, Chen J, Li B, Guo Z, Ye J.   +6 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Tartrate-Resistant Acid Phosphatase-Positive Cells: Putative Mediators of Peri-Implant Bone Healing. [PDF]

J Periodontal Res
Warda N, Noh R, Davies JE.
europepmc   +1 more source

Elusive physiological role of prostatic acid phosphatase (PAP): generation of choline for sperm motility via auto-and paracrine cholinergic signaling. [PDF]

Front Physiol, 2023
Hanley PJ.
europepmc   +1 more source