Results 51 to 60 of about 3,329,624 (262)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A study of the root surface phosphatase activities of three species of higher plants: Juncus effusus, Phragnutes australis, and Typha latifolia [PDF]
, 1993 The aim of this project was to investigate a possible link between environmental phosphorus status and the root surface phosphatase activities of three species of emergent macrophytes, with a view to assessing their potential for use as "biondicators ...
Luff, Heather
core
National Journal of Medical Research, 2015 Background: There are multiple diagnostic tests and procedures are available for diagnosis of infertility but semen analysis still is considered as most valuable diagnostic test for investigation of infertility.it is equally important that the semen ...
Nayak Jitendra +3 more
doaj
Plant, Soil and Environment, 2002 In barley roots significant increase of acid phosphatase activity was observed during Al treatment. Especially steep increase was found in the roots of Al-sensitive cv.
J. Huttová, L. Tamás, I. Mistrík
doaj +1 more source
Determination the activity of prostatic acid phosphatase women with breast cancer in Kirkuk City [PDF]
Kirkuk Journal of Science, 2017 The current study included estimation of Acid Phosphatase (AP) and Prostatic Acid Phosphatase (PAP) activity in the sera of Breast Cancer patient̓s. The study included (58) samples as satisfactory sample of women with breast cancer who are treated at ...
Ferah G. Al -Salihi +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2009 Background The HD-PTP protein has been described as a tumor suppressor candidate and based on its amino acid sequence, categorized as a classical non-transmembrane protein tyrosine phosphatase (PTP).
Kharitidi, D. +6 more
core +1 more source
Phosphatase activity of Poa pratensis seeds. I. Preliminary studies on acid phosphatase II
Acta Societatis Botanicorum Poloniae, 2015 Acid phosphatase (EC 3.1.3.2) was extracted with 0.1 M sodium acetate buffer pH 5.1 from Poa pratensis seeds, and separated into three fractions by chromatography on DEAE cellulose.
I. Lorenc-Kubis, B. Morawiecka
doaj +1 more source
The effect of different copper doses and organic fertilisation on soil's enzymatic activity
Plant, Soil and Environment, 2020 A three-year pot experiment carried out in the vegetation hall in 2014-2016 included studying the enzymatic activity of soil, into which various amounts of copper: (100, 200 and 300 mg Cu/kg soil) and organic materials (cattle manure, chicken manure ...
Beata Kuziemska +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source