Results 111 to 120 of about 802,100 (213)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Structural Evidence of Interanionic Hydrogen Bonding in Phosphoric Acid Solutions. [PDF]

J Am Chem Soc
Kim P, Kang R, Carter-Fenk K, Wilson KR, Head-Gordon M, Ahmed M.   +5 more
europepmc   +1 more source

Chitin Cryogels Prepared by Regeneration from Phosphoric Acid Solutions. [PDF]

Materials (Basel), 2021
Tyshkunova IV, Chukhchin DG, Gofman IV, Pavlova EN, Ushakov VA, Vlasova EN, Poshina DN, Skorik YA.   +7 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Assessing the hydrolysis of PDO threads combined with injectable hyaluronic acid solutions for facial rejuvenation. [PDF]

Braz Dent J
Delaroli FPB, Costa APC, Setti JBM, Freitas PM, Arana-Chavez VE, Lobo MM.   +5 more
europepmc   +1 more source

Spectral signatures of excess-proton waiting and transfer-path dynamics in aqueous hydrochloric acid solutions. [PDF]

Nat Commun, 2022
Brünig FN, Rammler M, Adams EM, Havenith M, Netz RR.   +4 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Sodium Dodecylbenzene Sulfonate-Mediated Self-Assembly of Silk Particles from Formic Acid Solutions into Robust Films. [PDF]

Polymers (Basel)
Malaspina R, Alunni Cardinali M, Libera V, Comez L, Petrillo C, Paciaroni A, Sassi P, Valentini L.   +7 more
europepmc   +1 more source

Evaluation of Non-Cross Linked Xeno-Free Hyaluronic Acid Solutions as Visco Elastic Biomaterials.

J Pharm Bioallied Sci, 2023
Mohan SP, Palaniappan A.
europepmc   +1 more source

Corrosion Behavior of the AlCoCrFeNi_2.1 Eutectic High-Entropy Alloy in Chloride-Containing Sulfuric Acid Solutions at Different Temperatures. [PDF]

Materials (Basel), 2022
Song L, Hu W, Zhang X, Liao B, Wan S, Kang L, Guo X.   +6 more
europepmc   +1 more source