Results 141 to 150 of about 803,542 (263)

Fast nanoparticle rotational and translational diffusion in synovial fluid and hyaluronic acid solutions. [PDF]

open access: yesSci Adv, 2021
Unni M   +13 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Bacteriological Assessment of Different Root Canal Irrigants

open access: yesJournal of Baghdad College of Dentistry
Aim of the study: To evaluate the antibacterial action of different root canal irrigants. Materials and method: By the use of the zone of inhibition method, sodium hypochlorite (2.5% and 5%), acetic acid (2%), sodium chloride solutions (5 and 10%), and ...
Hussain F Al-Huwaizi
doaj  

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