Results 111 to 120 of about 2,018,257 (280)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

不同包装形式对黑芝麻储藏过程中酸值变化的影响Effect of different packaging forms on acid value change of black sesame during storage

open access: yesZhongguo youzhi
旨在为延长黑芝麻保质期,维持其品质提供参考,以黑龙江省新鲜黑芝麻为研究对象,分别采用常规空气包装、真空包装、充氮气包装,透明、铝箔和黑色避光自封塑料袋包装,以及是否添加抗氧化剂的包装形式对黑芝麻进行储藏,考察不同包装形式对黑芝麻酸值的影响,并对黑芝麻粉碎后酸值变化进行研究。结果表明:黑芝麻敞开接触空气储存其酸值变化最大,其他包装方式均能达到延长保质期的目的;整体而言,真空环境的储存效果优于氮气和空气环境的,加抗氧化剂的储存效果优于不加抗氧化剂的;在加抗氧化剂及在空气环境不加抗氧化剂的条件下 ...
不同包装形式对黑芝麻储藏过程中酸值变化的影响Effect of different packaging forms on acid value change of black sesame during storage
doaj   +1 more source

The Nutritive Value of the Fatty Acid Fractions of Butter Fat

open access: bronze, 1940
Edward J. Schantz   +3 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Influence of Extraction Temperature on the Quality of Neem Seed Oil: Preliminary Investigation

open access: yesABUAD Journal of Engineering Research and Development
The storage of neem oil for a long time before usage comes along with challenge of quality retain ability of the oil; and the extraction methods can affect the quality of neem seed oil. This research work compared the mechanical expression method to the
John Goji Usman   +3 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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