Results 1 to 10 of about 2,971,993 (317)

Radiation therapy‐associated toxicity: Etiology, management, and prevention

open access: yesCa-A Cancer Journal for Clinicians, 2021
Radiation therapy (RT) is a curative treatment for many malignancies and provides effective palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT are not specific to tumor cells and may produce toxicity due to ...
Kyle Wang
exaly   +2 more sources

A review of cancer immunotherapy toxicity

open access: yesCa-A Cancer Journal for Clinicians, 2020
Cancer immunotherapies, including checkpoint inhibitors and adoptive cell therapy, manipulate the immune system to recognize and attack cancer cells.
Lucy Kennedy
exaly   +2 more sources

Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging

open access: yesArchives of Toxicology, 2023
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species (collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is characterized by low to mild levels of oxidants involved in the regulation of ...
K. Jomová   +6 more
semanticscholar   +1 more source

Mitochondrial Dysfunction as a Hallmark of Environmental Injury

open access: yesCells, 2021
Environmental factors including diet, sedentary lifestyle and exposure to pollutants largely influence human health throughout life. Cellular and molecular events triggered by an exposure to environmental pollutants are extremely variable and depend on ...
Carolina Duarte-Hospital   +9 more
doaj   +1 more source

Determination of eight high polar pesticide residues in vegetables and fruits by hydrophilic interaction liquid chromatography combined with ultra-performance liquid chromatography-tandem mass spectrometry

open access: yes环境与职业医学, 2022
BackgroundThe production and consumption of high polar pesticides in China are the largest in the world. Therefore, it is urgent to develop a method with fast analysis, large flux, and high accuracy to determine the residues of these pesticides in food ...
Yu’e JIN   +7 more
doaj   +1 more source

Individual and Combined Cytotoxic Effects of Co-Occurring Fumonisin Family Mycotoxins on Porcine Intestinal Epithelial Cell

open access: yesFoods, 2023
Human health is seriously threatened by mycotoxin contamination, yet health risk assessments are typically based on just one mycotoxin, potentially excluding the additive or competitive interactions between co-occurring mycotoxins. In this investigation,
Song Yu   +3 more
doaj   +1 more source

Distribution and health risk assessment of N-nitrosodimethylamine in urban drinking water in China

open access: yes环境与职业医学, 2021
BackgroundNitrosamines, especially N-nitrosodimethylamine (NDMA), are highly carcinogenic and frequently detected in drinking water systems in China, indicating potential human health risk through drinking water.ObjectiveThis study aims to analyze the ...
Hongquan CAI   +3 more
doaj   +1 more source

Effects of Munc13-1 and Munc18-1 on dopamine secretion dysfunction in manganese-exposed SH-SY5Y cells

open access: yes环境与职业医学, 2023
BackgroundNeurotransmitter secretion disorder induced by chronic manganese poisoning has always been one of the important causes of body injury, but the mechanism of neurotransmitter secretion disorder caused by manganese is not clear at present ...
Changzhe LI   +4 more
doaj   +1 more source

Hallmarks of response, resistance, and toxicity to immune checkpoint blockade

open access: yesCell, 2021
Unprecedented advances have been made in cancer treatment with the use of immune checkpoint blockade (ICB). However, responses are limited to a subset of patients, and immune-related adverse events (irAEs) can be problematic, requiring treatment ...
Golnaz Morad   +3 more
semanticscholar   +1 more source

Review on Methylene Blue: Its Properties, Uses, Toxicity and Photodegradation

open access: yesWater, 2022
The unavailability of clean drinking water is one of the significant health issues in modern times. Industrial dyes are one of the dominant chemicals that make water unfit for drinking.
Idrees Khan   +11 more
semanticscholar   +1 more source

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