Results 1 to 10 of about 1,536,167 (268)
Purpose of reviewOur aim is to highlight major advances reported in the last few years in drug-induced muscle toxicity.Recent findingsOur focus is on myopathies induced by statins and immune checkpoint inhibitors with a brief overview of rare steroid myopathies.
Mamatha, Pasnoor +2 more
openaire +3 more sources
‘Toxic worldings’: Introduction to toxic flows [PDF]
In the course of recent world history, humans have permanently changed the chemical composition of the planet, as human‐made chemical substances become part of the air, water and soil, pervading human and non‐human bodies and upsetting linear imaginaries of past and future.
Geissler, Paul Wenzel, Prince, Ruth Jane
openaire +2 more sources
Toxicity of nanomaterials [PDF]
Nanoscience has matured significantly during the last decade as it has transitioned from bench top science to applied technology. Presently, nanomaterials are used in a wide variety of commercial products such as electronic components, sports equipment, sun creams and biomedical applications.
Sharifi, S. +5 more
openaire +4 more sources
The first part of the present review deals with the chemical and enzymatic synthesis of adrenochrome and other aminochromes from the corresponding catecholamines. A description of the most significant pathways of formation and the reactivity of the aminochromes is presented.
BINDOLI, ALBERTO +2 more
openaire +3 more sources
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
How toxic is toxic? A proposal for wastewater toxicity hazard assessment
Wastewater management receives a great deal of attention with various methods being proposed for discharge hazard estimation via ecotoxicological results. Policy-makers, stakeholders and the general public do not generally possess an adequate level of understanding on this matter, so it is rather hard to answer the question "How toxic is toxic?".
LIBRALATO, Giovanni +2 more
openaire +3 more sources

