Results 41 to 50 of about 2,971,993 (317)

Oxidative damage in metal fragment-embedded Sprague-Dawley rat gastrocnemius muscle

Current Research in Toxicology, 2022
Injuries suffered in armed conflicts often result in wounds with embedded metal fragments. Standard surgical guidance has been to leave fragments in place except under certain circumstances; meaning that individuals may carry these retained fragments for
John F. Kalinich, Vernieda B. Vergara, Jessica F. Hoffman   +2 more
doaj   +1 more source

Immune-checkpoint inhibitors: long-term implications of toxicity

Nature Reviews Clinical Oncology, 2022
The development of immune-checkpoint inhibitors (ICIs) has heralded a new era in cancer treatment, enabling the possibility of long-term survival in patients with metastatic disease, and providing new therapeutic indications in earlier-stage settings. As
Douglas B. Johnson, C. Nebhan, J. Moslehi, J. Balko   +3 more
semanticscholar   +1 more source

Transcriptome Analysis of Thiram-Treated Zebrafish (Danio rerio) Embryos Reveals Disruption of Reproduction Signaling Pathways

Biology, 2023
Thiram, a dithiocarbamate fungicide, is used for the treatment of various fungal infections affecting crops and ornamentals. However, thiram-associated toxicity has been reported in animals, including fish, and the underlying molecular mechanisms are ...
Bala Murali Krishna Vasamsetti, Kyongmi Chon, Ji-Yeong Choi, Juyeong Kim, Chang-Young Yoon   +4 more
doaj   +1 more source

ProTox 3.0: a webserver for the prediction of toxicity of chemicals

Nucleic Acids Research
Interaction with chemicals, present in drugs, food, environments, and consumer goods, is an integral part of our everyday life. However, depending on the amount and duration, such interactions can also result in adverse effects.
Priyanka Banerjee, Emanuel Kemmler, Mathias Dunkel, R. Preissner   +3 more
semanticscholar   +1 more source

Toxicity of aminochromes

Toxicology Letters, 1989
The first part of the present review deals with the chemical and enzymatic synthesis of adrenochrome and other aminochromes from the corresponding catecholamines. A description of the most significant pathways of formation and the reactivity of the aminochromes is presented.
BINDOLI, ALBERTO, RIGOBELLO, MARIA PIA, GALZIGNA, LAURO   +2 more
openaire   +3 more sources

Overexpression of lncRNA IGFBP4–1 reprograms energy metabolism to promote lung cancer progression

Molecular Cancer, 2017
Background Reprogrammed energy metabolism as an emerging hallmark of cancer has recently drawn special attention since it facilitate cell growth and proliferation.
Binyao Yang, Lisha Zhang, Yi Cao, Shuai Chen, Jun Cao, Di Wu, Jiansong Chen, Huali Xiong, Zihua Pan, Fuman Qiu, Jinbin Chen, Xiaoxuan Ling, Maosheng Yan, Suli Huang, Shiyu Zhou, Tiegang Li, Lei Yang, Yunchao Huang, Jiachun Lu   +18 more
doaj   +1 more source

Toxicity of metal-based nanoparticles: Challenges in the nano era

Frontiers in Bioengineering and Biotechnology, 2022
With the rapid progress of nanotechnology, various nanoparticles (NPs) have been applicated in our daily life. In the field of nanotechnology, metal-based NPs are an important component of engineered NPs, including metal and metal oxide NPs, with a ...
Nai-shun Zhang, Guiya Xiong, Zhenjie Liu
semanticscholar   +1 more source

A comprehensive method for determination of 55 traditional and emerging per- and polyfluoroalkyl substances in infant complementary foods using liquid chromatography-high resolution mass spectrometry

环境与职业医学
BackgroundPer- and polyfluoroalkyl substances (PFASs) are a class of persistent organic pollutants that pose potential health risks to humans. Infants and young children have higher requirements for food safety due to the underdeveloped detoxification ...
Ziwei LIANG, Chao FENG, Jiawen YOU, Zixin QIAN, Sunyang LE, Dasheng LU   +5 more
doaj   +1 more source

Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations

Beilstein Journal of Nanotechnology, 2018
Nanomaterials (NMs) have gained prominence in technological advancements due to their tunable physical, chemical and biological properties with enhanced performance over their bulk counterparts.
J. Jeevanandam, Ahmed Barhoum, Y. S. Chan, A. Dufresne, M. Danquah   +4 more
semanticscholar   +1 more source

An AOP-Based Integrated In Vitro and In Vivo Assessment of the Non-Genotoxic Carcinogenic Potential of Multi-Walled Carbon Nanotubes

Nanomaterials
Multi-walled carbon nanotubes (MWCNTs) are increasingly incorporated into industrial and consumer products, raising concerns about potential carcinogenicity because their physicochemical properties vary widely among materials.
Minju Kim, Heesung Hwang, Sulhwa Song, Keun-Soo Kim, JuHee Lee, Seung Min Oh   +5 more
doaj   +1 more source