Results 61 to 70 of about 2,971,993 (317)

How toxic is toxic? A proposal for wastewater toxicity hazard assessment

Ecotoxicology and Environmental Safety, 2010
Wastewater management receives a great deal of attention with various methods being proposed for discharge hazard estimation via ecotoxicological results. Policy-makers, stakeholders and the general public do not generally possess an adequate level of understanding on this matter, so it is rather hard to answer the question "How toxic is toxic?".
LIBRALATO, Giovanni, AVEZZU', Francesco, VOLPI GHIRARDINI, Annamaria   +2 more
openaire   +3 more sources

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Horizontal Honey-Bee Larvae Rearing Plates Can Increase the Deformation Rate of Newly Emerged Adult Honey Bees

Insects, 2021
Rearing honey bee larvae in vitro is an ideal method to study honey bee larval diseases or the toxicity of pesticides on honey bee larvae under standardized conditions. However, recent studies reported that a horizontal position may cause the deformation
Juyeong Kim, Kyongmi Chon, Bo-Seon Kim, Jin-A Oh, Chang-Young Yoon, Hong-Hyun Park, Yong-Soo Choi   +6 more
doaj   +1 more source

The Toxicity of Mercury and Its Chemical Compounds: Molecular Mechanisms and Environmental and Human Health Implications: A Comprehensive Review

ACS Omega
Mercury is a type of hazardous and toxic pollutant that can result in detrimental effects on the environment and human health. This review is aimed at discussing the state-of-the-art progress on the recent developments on the toxicity of mercury and its ...
Y. Wu, Ahmed I. Osman, M. Hosny, A. Elgarahy, Abdelazeem S. Eltaweil, David W. Rooney, Zhonghao Chen, Nur Syafiqah Rahim, M. Sekar, S. Gopinath, Nur Najihah Izzati Mat Rani, K. Batumalaie, P. Yap   +12 more
semanticscholar   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Flurochloridone induces responses of free radical reactions and energy metabolism disorders to BRL-3A cell

Ecotoxicology and Environmental Safety, 2022
Flurochloridone (FLC), a wildly used herbicide, could induce hepatotoxicity after long-term exposure to male rat, in addition to its reactive oxygen species (ROS)-dependent reproductive toxicity.
Liming Xue, Jiale Xu, Chao Feng, Zhijun Zhou, Yu’e Jin, Dasheng Lu, Guoquan Wang   +6 more
doaj   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex, Sean P. Hassan, Helen Benghiat, Liam Herbert, Jennifer Adamski, Shivani Bailey, Claire Esler, Louise Brookes, Molly Bamber, Grace Koudou, Karen Waite, Julie Bennett, Anirban Das, Derek S. Tsang   +13 more
wiley   +1 more source

Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology

Journal of Toxicology, 2021
Nanoparticles are of great importance in development and research because of their application in industries and biomedicine. The development of nanoparticles requires proper knowledge of their fabrication, interaction, release, distribution, target ...
Chukwuebuka Egbuna, Vijaykumar K. Parmar, J. Jeevanandam, S. Ezzat, K. Patrick-Iwuanyanwu, C. Adetunji, Johra Khan, E. N. Onyeike, Chukwuemelie Z. Uche, M. Akram, M. Ibrahim, Nihal M. El Mahdy, C. G. Awuchi, K. Saravanan, H. Tijjani, U. Odoh, M. Messaoudi, J. C. Ifemeje, M. Olisah, N. Ezeofor, C. J. Chikwendu, C. Ibeabuchi   +21 more
semanticscholar   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Environmental source, fate, and toxicity of microplastics.

Journal of Hazardous Materials, 2020
Microplastics are small plastic pieces with sizes less than 5 mm. Due to their widespread distribution in different environmental compartments, food, and drinking water, microplastics have attracted increasing attention across the world. Previous reports
Chunhui Wang, Jian Zhao, B. Xing
semanticscholar   +1 more source