Results 61 to 70 of about 1,536,167 (268)
, 1957 Two aqueous suspensions, one containing crystals of uniform size and the other containing colloidal particles, were made with each of seven solid contact poisons (two DDT-analogues, DDT, rotenone, 2-bromomercurithiophen, dieldrin and endrin).
Mcintosh, A. H.
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Toxicity of Triphenyltin [PDF]
Occupational and Environmental Medicine, 1966 The toxicity of triphenyltin has been determined after its acute oral and intraperitoneal administration in rats, guinea-pigs, rabbits, mice, and hens, after feeding it to rats and guinea-pigs, and after its application to the skin of guinea-pigs.
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2000 Toxicity of dissolved copper was examined in a common coastal mysid population {Praunusflexuosus}. The life cycle and ecophysiology were studied under natural conditions throughout the year, and responses to dissolved copper were determined in the ...
Garnacho, Eva
core
The Dynamics and Toxicity of Quantum Dots in the Caenorhabditis Elegans Embryo [PDF]
, 2009 Quantum dots are semiconductor nanocrystals with unique optical properties that give them the potential to be excellent probes for bio-imaging applications.
Shehata, Shyemaa
core
Review of the methods to determine the hazard and toxicity of pesticides to bumblebees
, 2001 Methods to determine the impact of pesticides on bumblebees are described. They are classified into laboratory tests to determine the acute toxicity and the hazard to bumblebees, (semi) field tests, and brood tests.
Steen, J.J.M., van der +3 more
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source