Results 11 to 20 of about 2,971,993 (317)

Assessment of respiratory and systemic toxicity of Benzalkonium chloride following a 14-day inhalation study in rats

open access: yesParticle and Fibre Toxicology, 2020
Background Although biocides at low concentrations have been used to control pests, they can be more harmful than industrial chemicals as humans are directly and frequently exposed to such biocides.
Hye-Yeon Choi   +9 more
doaj   +1 more source

Cadmium toxicity in plants: Impacts and remediation strategies.

open access: yesEcotoxicology and Environmental Safety, 2021
Cadmium (Cd) is an unessential trace element in plants that is ubiquitous in the environment. Anthropogenic activities such as disposal of urban refuse, smelting, mining, metal manufacturing, and application of synthetic phosphate fertilizers enhance the
F. Haider   +7 more
semanticscholar   +1 more source

Humidifier disinfectant, sodium dichloroisocyanurate (NaDCC): assessment of respiratory effects to protect workers’ health

open access: yesScientific Reports, 2021
In South Korea, it has been found that biocides used to control and eliminate harmful organisms are used as humidifier disinfectants and cause lung disease in users.
DongSeok Seo, Yong-Hoon Lee, JiMin Jo
doaj   +1 more source

Effect of embedded metal fragments on urinary metal levels and kidney biomarkers in the Sprague-Dawley rat

open access: yesToxicology Reports, 2021
Background: Wounds with embedded metal fragments are an unfortunate consequence of armed conflicts. In many cases the exact identity of the metal(s) and their long-term health effects, especially on the kidney, are not known.
Jessica F. Hoffman   +3 more
doaj   +1 more source

Antioxidant Activities of Natural Compounds from Caribbean Plants to Enhance Diabetic Wound Healing

open access: yesAntioxidants, 2023
Diabetic wound healing is a global medical challenge. Several studies showed that delayed healing in diabetic patients is multifactorial. Nevertheless, there is evidence that excessive production of ROS and impaired ROS detoxification in diabetes are the
Laura Accipe   +3 more
doaj   +1 more source

hTERT DNA Methylation Analysis Identifies a Biomarker for Retinoic Acid-Induced hTERT Repression in Breast Cancer Cell Lines

open access: yesBiomedicines, 2022
Telomerase reactivation is responsible for telomere preservation in about 90% of cancers, providing cancer cells an indefinite proliferating potential.
Eric Nguyen   +4 more
doaj   +1 more source

Toxicity of nanomaterials [PDF]

open access: yesChem. Soc. Rev., 2012
Nanoscience has matured significantly during the last decade as it has transitioned from bench top science to applied technology. Presently, nanomaterials are used in a wide variety of commercial products such as electronic components, sports equipment, sun creams and biomedical applications.
Sharifi, S.   +5 more
openaire   +4 more sources

Evaluation of mutagenicity of zinc oxide nanoparticles by Pig-a mutation assay in vivo

open access: yesShanghai yufang yixue, 2022
ObjectiveThe genotoxicity of zinc oxide nanoparticles (ZnO NPs) in rats was determined by Pig⁃a mutation assay in vivo.MethodsCombined with 28-day oral toxicity test, male SD rats were given ZnO NPs by oral administration for 28 days, at doses of 0, 14 ...
CHENG Xueqing   +4 more
doaj   +1 more source

Acute and Subchronic Inhalation Toxicity of n-Octane in Rats

open access: yesSafety and Health at Work, 2010
Objectives: We have investigated the toxic effects of the inhalation of subchronic and acute levels of n-octane. Methods: The rats were exposed to n-octane of 0, 2.34, 11.68 and 23.36 mg/L (n = 5 rats/group/gender) in an acute inhalation test ...
Jae Hyuck Sung   +8 more
doaj   +1 more source

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

open access: yesJournal of Medicinal Chemistry, 2015
Drug development has a high attrition rate, with poor pharmacokinetic and safety properties a significant hurdle. Computational approaches may help minimize these risks.
Douglas E. V. Pires   +2 more
semanticscholar   +1 more source

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