Results 161 to 170 of about 20,083,260 (392)

Comparative Feeding Value of Lactic Acid and Grain for Dairy Cattle [PDF]

open access: bronze, 1961
R.S. Emery   +5 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Studying the Effect of Cultivars and Storage Time on Oxidative Parameters of Pistachio Oil through Response Curves

open access: yesJournal of Nuts
Pistachio oil is golden yellow or greenish yellow in color, contains a variety of beneficial fatty acids and is obtained from pistachio kernel extract, which has numerous nutritional value and therapeutic properties.
Seyed Mehdi Mousavi   +2 more
doaj  

The Value of Tranexamic Acid in Reducing Blood Loss following Hip Reconstruction in Children with Cerebral Palsy [PDF]

open access: hybrid, 2015
Ibrar Majid   +4 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Discussion on the Scientific Connotation of Acid Value Indicators in Edible Vegetable Oils and Limitations of Current Detection Methods

open access: yesLiang you shipin ke-ji
This paper discusses the causes of high acid value in crude plant oils and finished oils, the regulatory limits of acid value indicators for crude plant oils, refined finished oils, and frying oils, as well as the limitations of current acid value ...
JIN Qing-zhe   +3 more
doaj   +1 more source

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