Results 171 to 180 of about 1,959,839 (301)

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

open access: yesAdvanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen   +4 more
wiley   +1 more source

Figure 1. The pH Scale (Source: NCSA). Causes of Soil Acidity [PDF]

open access: yes
Soil acidity refers to the level of acids present in soils. As acid levels increase, the pH of the soil decreases. While the pH scale ranges from 0-14, most Tennessee soils range in value from 4.5 to 7.5.
In Tennessee, Debbie Joines, Ut Soil
core  

Inoculation of Bacillus subtilis in acidic soil amended with biochar and liming materials in maize cultivation. [PDF]

open access: yesSci Rep
Diaz-Chuquizuta H   +7 more
europepmc   +1 more source

The Potential of Self‐Maintainable Living Materials

open access: yesAdvanced Science, EarlyView.
Self‐maintainable living materials are presented as the next generation of bioadaptive systems, integrating continuous sensing, decision‐making, response, self‐repair, and adaptation in a closed‐loop framework. This review highlights the design principles and emerging technologies that enable autonomous, long‐term functionality for future regenerative ...
Mohammadsadegh Nadimifar   +4 more
wiley   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao   +7 more
wiley   +1 more source

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