Results 181 to 190 of about 2,919 (292)

Orthogonal Design of Competing Deprotonation Process in Cation‐Mediated Ni(OH)2 for Achieving Industrial Level Biomass Electrooxidation

open access: yesAdvanced Science, EarlyView.
A Cu‐mediated Ni(OH)2 catalyst with orthogonal activity by precise valence engineering simultaneously accelerates rate‐determining aldehyde C─H activation in HMF oxidation and impedes O─H deprotonation in competing OER. This multi‐functional synergistic catalysis enables FDCA production at industrial‐level current densities without sacrificing FEFDCA ...
Junge Yang   +7 more
wiley   +1 more source

Supplemental effects of acidifier and encapsulated butyrate solely and combined in high canola meal diets for nursery pigs. [PDF]

open access: yesJ Anim Sci
McClellan KA   +8 more
europepmc   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

open access: yesAdvanced Science, EarlyView.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu   +7 more
wiley   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

open access: yesAdvanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo   +7 more
wiley   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

open access: yesAdvanced Science, EarlyView.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang   +9 more
wiley   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang   +9 more
wiley   +1 more source

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