Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Chemical Recycling of Polyesters and Polycarbonates: Why Is Zinc(II) Such an Effective Depolymerization Catalyst? [PDF]
McGuire TM, Buchard A, Williams CK.
europepmc +1 more source
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Impact of Coffee Cherry Fermentation Methods on the Quality Attributes of Dry-Processed Coffee. [PDF]
Moncayo-Palacios MF +4 more
europepmc +1 more source
Autophagy and apoptosis in the oxidative stress protection of extracellular acidity
Nur Kaluç +2 more
openalex +2 more sources
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Analyzing the Solvent Effects in Palladium/<i>N</i>-Heterocyclic Carbene (Pd/NHC)-Catalyzed Suzuki-Miyaura Coupling of Aryl Chlorides: A Computational Study of the Oxidative Addition Step with Experimental Validation. [PDF]
Collier M +6 more
europepmc +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Increased PM<sub>2.5</sub> Caused by Enhanced Fireworks Burning and Secondary Aerosols in a Forested City of North China During the 2023-2025 Spring Festivals. [PDF]
Ma Q +10 more
europepmc +1 more source
Critical loads in freshwater ecosystems (1995-1998): a summary report to DETR [PDF]
Allott, T.E.H. +8 more
core

