Results 141 to 150 of about 98,978 (269)

Prolonged Gastrointestinal Transit Times and Dysmotility in m.3243A>G Mitochondrial Disease

open access: yesNeurogastroenterology &Motility, EarlyView.
Carriers of m.3243A>G mitochondrial disease have impaired mitochondrial adenosine triphosphate (ATP) production. Our findings indicate that patients exhibit gastrointestinal dysmotility as assessed by the wireless motility capsule SmartPill. This indicates a critical role of mitochondrial ATP in normal gastrointestinal function.
Simone Rask Nielsen   +6 more
wiley   +1 more source

The Landscape of Cancer Metabolism as a Therapeutic Target

open access: yesPathology International, EarlyView.
ABSTRACT Cancer cells reprogram their metabolism during progression to adapt to the tumor microenvironment, which is characterized by distinct differences in nutrient availability, oxygen concentrations, and acidity. This metabolic reprogramming can simultaneously create metabolic vulnerabilities unique to cancer cells, making cancer metabolism a ...
Kenji Ohshima
wiley   +1 more source

Cardiopulmonary resuscitation in anaesthetised foals

open access: yes
Equine Veterinary Education, EarlyView.
K. Varner, H. Roessner
wiley   +1 more source

Delayed Zinc Phosphide Toxicosis in a Dog

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective Zinc phosphide is a widely used, commercial, non‐anticoagulant rodenticide. However, there is a lack of detailed information in veterinary literature regarding its toxic effects. The purpose of this case report is to provide a comprehensive description of toxicosis caused by zinc phosphide in a dog that underwent early ...
Saskia van Schie   +2 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr   +2 more
wiley   +1 more source

Subperiosteal Hematoma of orbit an interesting case report and review of literature [PDF]

open access: yes
Subperiosteal Hematoma orbit is an uncommon disorder which may occur following injury to orbit.\ud Ofcourse there are other causes that cause this condition as well. This condition has been reported\ud in young adults.
Balasubramanian, Thiagarajan
core  

Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas

open access: yesExperimental Physiology, EarlyView.
Abstract Moderate and acute intermittent hypoxia (IH) facilitates respiration in adults, mostly by recruiting peripheral chemo‐/baroreceptors. As central chemoreceptors are widely expressed in immature brains, we hypothesized that IH modulates respiration at birth through a purely neurogenic mechanism involving the hypothalamus.
Rosamaria Apicella   +2 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker   +2 more
wiley   +1 more source

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