Results 111 to 120 of about 171,422 (307)

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

G91-1047 Acidosis [PDF]

open access: yes, 1991
This NebGuide discusses why acidosis occurs, its economic considerations, and methods to prevent and treat acidosis. Acidosis is the most important nutritional disorder in feedlots today.
Britton, Robert, Stock, Rick
core  

Nanoagonist‐mediated spatiotemporal reprogramming of macrophage phenotypes to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang   +7 more
wiley   +1 more source

ACIDOSIS IN SHOCK [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1918
At the suggestion of the National Research Council, extensive investigations on shock have been undertaken. Numerous theories have been offered as to the cause of the condition termed "shock." One attributes the condition to acidosis, and sodium bicarbonate has been suggested in the treatment.
openaire   +2 more sources

The Treatment of Diabetic Acidosis [PDF]

open access: yes, 1966
The patient with diabetes mellitus who becomes unconscious presents a problem in differential diagnosis. We now recognize six possible causes of coma in the diabetic patient.
Danowski, Thaddeus S.
core  

Pyroglutamic acidosis in a renal transplant patient

open access: yes, 2005
Metabolic acidosis is a common acid–base disorder in critically ill patients. Elucidation of the cause usually commences with the calculation of the anion gap.
Mullany, Daniel V.   +2 more
core   +1 more source

Non‐contrast MRI reliably captures perfusion abnormalities in status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...
Lukas Machegger   +5 more
wiley   +1 more source

Studies of acidosis: I. The bicarbonate concentration of the blood plasma; its significance, and its determination as a measure of acidosis

open access: yes, 1917
STUDIES OF ACIDOSIS: I. THE BICARBONATE CONCENTRATION OF THE BLOOD PLASMA; ITS SIGNIFICANCE, AND ITS DETERMINATION AS A MEASURE OF ACIDOSIS Studies of acidosis: I.
Slyke, Donald D. van Glenn E. Cullen
core   +2 more sources

Nasal high-flow in acute hypercapnic exacerbation of COPD

open access: yesInternational Journal of COPD, 2018
Jens Bräunlich, Hubert Wirtz Department of Respiratory Medicine, University of Leipzig, Leipzig, Germany Since the late 1980s non-invasive ventilatory support (NIV) has become a standard treatment in acute exacerbation of COPD (AECOPD) with ...
Bräunlich J, Wirtz H
doaj  

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