Results 141 to 150 of about 134,882 (291)

Role of the DPP4 Receptor in SARS‐CoV Entry: Insights From Docking and Molecular Dynamics Simulations

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein–receptor interactions play a critical role in viral entry and pathogenesis. While ACE2 is the primary receptor for SARS‐CoV, the role of DPP4 as potential coreceptor remains underexplored. This study investigates the binding mechanisms and dissociation dynamics of the SARS‐CoV/DPP4, SARS‐CoV/ACE2 and MERS‐CoV/DPP4 complexes using ...
Patrícia Pereira Duzi Carvalho, Nelson Augusto Alves   +1 more
wiley   +1 more source

Euglycemic Diabetic Ketoacidosis Triggered by Sepsis in a Patient on Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitor Therapy: A Case of Diagnostic and Therapeutic Challenges. [PDF]

Cureus
Ramalingam A, Tewadros A, De Souza Goncalves B, Yelangi A, Elghul A.   +4 more
europepmc   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Systematic review and meta-analysis of current guidelines, and their evidence base, on risk of renal function after administration of contrast medium for diabetic patients receiving metformin. [PDF]

Front Med (Lausanne)
Xu Q, Huang W, Li Q, Bao T, Luo H, Luo X.   +5 more
europepmc   +1 more source

CLINICAL SIGNIFICANCE OF RESPIRATORY ACIDOSIS DURING OPERATIONS*

, 1951
Herbert C. Maier, George W. Rich, Seymour Eichen   +2 more
openalex   +2 more sources

ACIDOSIS AND THE NITROGEN PARTITION IN PREGNANCY [PDF]

, 1915
H. L. Murray
openalex   +1 more source

Polyglycerol‐Grafted Graphene Oxide with pH‐Responsive Charge‐Convertible Surface to Dynamically Control the Nanobiointeractions for Enhanced in Vivo Tumor Internalization

Small, EarlyView.
Polyglycerol‐grafted graphene oxide with three increasing amounts of amino functions, modified with the pH sensitive dimethylmaleic anhydride, displays higher physiological stability as the density of the functional groups decreases, while their cancer cell uptake follows the opposite trend.
Yajuan Zou, Alberto Bianco, Yuta Nishina
wiley   +1 more source

Real-time magnetic resonance visualization of tumor acidosis as a precognition indicator of therapeutic efficacy. [PDF]

Bioact Mater
Mu M, Zhang M, Liu J, Ren K, Liu H, Yip L, Guo K, Teng F, Dong J, Xu X, Leong DT, Sun X.   +11 more
europepmc   +1 more source

THE SIGNIFICANCE OF ACIDOSIS IN CERTAIN NERVOUS DISORDERS [PDF]

, 1920
Beth Shaw
openalex   +1 more source

Solution‐Processed Diode‐Like ZnO Nanoparticle Device with Tunable Threshold Voltage and Super‐Nernstian Ion Sensitivity

Small, EarlyView.
The working function of ZnO NPs diode‐like devices and their ion sensing applications. This structure is achieved by modulating the ionized adsorbed oxygen molecules on the ZnO NPs surface. The adsorption and desorption can be controlled by the external electrical field to switch on and off.
Mengyang Qu, Huanghao Dai, Omesh R. Kapur, Stephen P. Beeby, Harold M. H. Chong   +4 more
wiley   +1 more source