Severe Suspected Metformin-Associated Lactic Acidosis With Relatively Preserved Serum Creatinine at Presentation: Sequential Intermittent Hemodialysis and Continuous Venovenous Hemodialysis. [PDF]
Hassanein M, Rodriguez C, Lentine KL.
europepmc +1 more source
Fenestrated Microneedle Biosensor for Continuous In Vivo Lactate Monitoring in Interstitial Fluid
A fenestrated microneedle biosensor enables continuous transdermal monitoring of lactate in interstitial fluid while protecting the functional sensing interface during insertion into the skin. The platform delivers sensitive electrochemical lactate detection and distinguishes metabolic profiles in healthy and type 2 diabetic‐obese mice, and captures ...
Masoud Khazaei +5 more
wiley +1 more source
Modified, bicarbonate-augmented direct peritoneal resuscitation for refractory acidosis after damage control laparotomy: a single-center case series. [PDF]
Mast G, Carver R, Rice WM, Burgess J.
europepmc +1 more source
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source
Persistent metabolic acidosis and frailty trajectories after kidney transplantation: a prospective cohort study. [PDF]
Siriteanu L +5 more
europepmc +1 more source
Advances in research on layered double hydroxides for biomedical applications
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Defying An Ominous Sign: Complete Neurological Recovery after Bilateral Fixed Dilated Pupils in Hypercapnic Respiratory Failure. [PDF]
Naimer SA.
europepmc +1 more source
Acidic pH triggers GOT1 phase separation via IDR1, recruiting ME1 to form ROS‐scavenging condensates that combat senescence, revealed by a FLIM‐based pH probe. Abstract Cellular senescence involves progressive acidification, but how cells sense and adapt to this pH shift remains unclear.
Ziyue Chen +8 more
wiley +1 more source

