Results 191 to 200 of about 171,422 (307)

Fenestrated Microneedle Biosensor for Continuous In Vivo Lactate Monitoring in Interstitial Fluid

open access: yesSmall, EarlyView.
A fenestrated microneedle biosensor enables continuous transdermal monitoring of lactate in interstitial fluid while protecting the functional sensing interface during insertion into the skin. The platform delivers sensitive electrochemical lactate detection and distinguishes metabolic profiles in healthy and type 2 diabetic‐obese mice, and captures ...
Masoud Khazaei   +5 more
wiley   +1 more source

Acidosis of Hypothermia

open access: yesAnnals of Surgery, 1961
W F, Ballinger   +3 more
openaire   +3 more sources

Targeting the Subthalamic Nucleus in MEGDEL Syndrome: A Case Report of a Clinically Effective Intervention for Debilitating Lingual Dyskinesia and Dystonia

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Philipp Köberle   +9 more
wiley   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

open access: yesSmart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu   +7 more
wiley   +1 more source

Persistent metabolic acidosis and frailty trajectories after kidney transplantation: a prospective cohort study. [PDF]

open access: yesClin Exp Nephrol
Siriteanu L   +5 more
europepmc   +1 more source

Advances in research on layered double hydroxides for biomedical applications

open access: yesSmart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang   +13 more
wiley   +1 more source

A pH‐Responsive fluorescence lifetime probe reveals GOT1 phase separation in cellular anti‐senescence

open access: yesSmart Molecules, EarlyView.
Acidic pH triggers GOT1 phase separation via IDR1, recruiting ME1 to form ROS‐scavenging condensates that combat senescence, revealed by a FLIM‐based pH probe. Abstract Cellular senescence involves progressive acidification, but how cells sense and adapt to this pH shift remains unclear.
Ziyue Chen   +8 more
wiley   +1 more source

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