Results 131 to 140 of about 9,916,530 (325)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Grain legumes and human health [PDF]

open access: yes, 2009
Since early civilisation in different continents, grain legumes have been a part of balanced diets together with cereals. In general the seeds from those two plant families give together a good source of essential amino acids and may have given an ...
Enneking, Dirk   +4 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Modification of Aminoacyl tRNA Synthetase in Order to Incorporate an Unnatural Amino Acid [PDF]

open access: yes, 2018
Proteins allow daily processes in the cell to occur. A protein consists of amino acids. There are twenty natural amino acids coded for in the DNA of organisms. The natural amino acids can be modified to form unnatural amino acids (UAAs). UAAs have useful
Burkhart, Grace
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Exploring RNA modifications in infectious non-coding circular RNAs

open access: yesRNA Biology
Viroids, small circular non-coding RNAs, act as infectious pathogens in higher plants, demonstrating high stability despite consisting solely of naked RNA.
Pavel Vopalensky   +8 more
doaj   +1 more source

Impact of a new nucleo-cytoplasmic composition on the citrus fuit quality : [23] [PDF]

open access: yes, 2008
Organic acids, sugars and carotenoids are implied in the fruit quality. A cybrid has been obtained by symmetric protoplast fusion between Willow leaf mandarin (Citrus deliciosa Ten.) and Eureka lemon (Citrus limon (L.) Buno.).
Bassene, Jean Baptiste   +7 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

MODIFICATION OF THE N-3 POLYUNSATURATED FATTY ACIDS CONTENT IN MUSCLE TISSUE OF PIGS [PDF]

open access: yesPoljoprivreda, 2013
The objective of the research was to find out which combinations of oils give a desirable effect on n-3 PUFA content modification and total values increase in pigs’ meat without negative effects on fattening characteristics and carcass and meat quality ...
Miljenko Ernoić
doaj  

Examining the PM6 semiempirical method for pKa prediction across a wide range of oxyacids [PDF]

open access: yes, 2009
The pK~a~ estimation ability of the semiempirical PM6 method was evaluated across a broad range of oxyacids and compared to results obtained using the SPARC software program.
Kaya Forest   +2 more
core   +1 more source

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