Results 251 to 260 of about 9,916,530 (325)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Correction to 'TDG orchestrates ATF4-dependent gene transcription during retinoic acid-induced cell fate acquisition'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Cancer-associated fibroblasts as key regulators of lipid metabolism in the tumour microenvironment. [PDF]

Oncogene
Adams J, Suelzu CM, Strusi G, Stebbing J.   +3 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Utilization, metabolic regulation and applications of hydrophobic substrates in <i>Yarrowia lipolytica</i>. [PDF]

Synth Syst Biotechnol
Zhu F, Zhang L, Wen J.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Integrated Metabolomic Profiling and Harvest Volatile Signatures Reveal Cultivar-Specific Quality Traits in Blueberries (<i>Vaccinium corymbosum</i> L.). [PDF]

Plants (Basel)
Kyrou MR, Stouris D, Besis A, Papathanasiou F, Karagiannis E.   +4 more
europepmc   +1 more source

Editorial: Omega-3 fatty acids and immunometabolism in health and disease. [PDF]

Front Nutr
Nunes EA, Yamazaki RK, de Brito GAP.
europepmc   +1 more source

First-Trimester Serum n-3/n-6 Fatty Acids Predict Large-for-Gestational-Age Risk: A Nested Case-Control Study. [PDF]

Matern Child Nutr
Cai X, Zhu H, Liang N, Zhu Y, Dang Q, Gao M, Yu H.   +6 more
europepmc   +1 more source